PMID: 43961Nov 1, 1979

Unimportance of perivascular H+ AND K+ activities for the adjustment of pial arterial diameter during changes of arterial blood pressure in cats

Pflügers Archiv : European journal of physiology
M Wahl, W Kuschinsky

Abstract

The role of perivascular H+ and K+ in the adjustment of pial arterial diameter during changes in arterial blood pressure was investigated in chloralose anesthetized cats. Blood pressure was reduced by i.v. mecamylamine or pentolinium and was increased by i.v. hypertensin. Pial arterioles and arteries with a control diameter ranging from 37--218 microns at a spontaneous mean arterial blood pressure of 128 +/- 16 (SD) mm Hg were studied. Vascular diameter as measured by TV image splitting showed the typical reactions, i.e. constriction during increase (up to 200 mm Hg) and dilation during decrease in blood pressure (down to 60 mm Hg). Perivascular H+ and K+ activities were measured using pH microelectrodes (Hinke type) and K+ ion exchanger microelectrodes, respectively. Under control conditions perivascular pH was 7.25 +/- 0.11 (SD) and K+ activity was 2.46 +/- 0.65 (SD) mM, respectively. During changes in blood pressure the vascular reactions of pial arteries were not accompanied by significant alterations in perivascular H+ or K+ activity. From these data it can be concluded that mechanisms other than those which are mediated by H+ or K+ are involved in the adjustment of pial arterial diameter during changes in arterial blood p...Continue Reading

References

Sep 1, 1976·The American Journal of Physiology·M J Hernandez-Perez, D K Anderson
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Citations

Jun 1, 1983·Naunyn-Schmiedeberg's Archives of Pharmacology·E T Whalley, M Wahl
Jul 1, 1980·Pflügers Archiv : European journal of physiology·P C GregoryA M Harper
May 1, 1984·Journal of Neurosurgery·B K Siesjö
Nov 1, 1981·Progress in Cardiovascular Diseases·R M BerneR Rubio
Jan 1, 1981·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J D Pickard
Dec 1, 1982·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R Sercombe, M Wahl
Jan 1, 1981·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·M L Craigen, S Jennett
Jan 1, 1981·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·H R WinnR M Berne
Jun 1, 1983·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·M WahlF Wagner
Nov 1, 1995·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A R ShahedP M Werchan
Dec 1, 1984·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A UnterbergA Baethmann
Jan 1, 1981·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·P M GrossG M Teasdale
Sep 1, 1985·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·M Wahl
Jun 1, 1984·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·E Leniger-Follert
Jan 1, 1982·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·E Dóra, A G Kovách
Jan 1, 1985·Annals of Biomedical Engineering·D R Harder
Mar 28, 1998·Acta Neurologica Scandinavica·C Berger, R von Kummer

Related Concepts

Angiotensin II, Val(5)-
Metazoa
Arteries
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Brain
Felis catus
Hydrogen-Ion Concentration
Mecamylamine
Pentolinium
Potassium

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