UniProt Knowledgebase: a hub of integrated protein data

Database : the Journal of Biological Databases and Curation
Michele Magrane, Uniprot Consortium


The UniProt Knowledgebase (UniProtKB) acts as a central hub of protein knowledge by providing a unified view of protein sequence and functional information. Manual and automatic annotation procedures are used to add data directly to the database while extensive cross-referencing to more than 120 external databases provides access to additional relevant information in more specialized data collections. UniProtKB also integrates a range of data from other resources. All information is attributed to its original source, allowing users to trace the provenance of all data. The UniProt Consortium is committed to using and promoting common data exchange formats and technologies, and UniProtKB data is made freely available in a range of formats to facilitate integration with other databases. Database URL: http://www.uniprot.org/


Jul 1, 1993·Nucleic Acids Research·D BensonJ Ostell
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
May 1, 1999·Bioinformatics·W FleischmannR Apweiler
Aug 31, 2000·Journal of Molecular Biology·C NotredameJ Heringa
Oct 23, 2001·BMC Bioinformatics·R D DowellL Stein
Apr 23, 2002·Pharmacogenomics·Cédric Notredame
Jun 12, 2003·Computational Biology and Chemistry·Alexandre GattikerAmos Bairoch
Mar 23, 2004·Nucleic Acids Research·Robert C Edgar
Mar 27, 2004·Bioinformatics·Rasko LeinonenRolf Apweiler
May 21, 2005·Bioinformatics·Philip JonesRolf Apweiler
Sep 6, 2007·PLoS Computational Biology·Cédric Notredame
Nov 16, 2007·Nucleic Acids Research·L G WilmingJ L Harrow
Apr 9, 2008·Bioinformatics·Samuel PatientRolf Apweiler
Jul 19, 2008·BMC Bioinformatics·Adel Golovin, Kim Henrick
Aug 13, 2008·Bioinformatics·Rafael C JimenezHenning Hermjakob
Oct 18, 2008·Nucleic Acids Research·Kim D PruittDonna R Maglott
Oct 23, 2008·Nucleic Acids Research·Sarah HunterCorin Yeats
Oct 25, 2008·Nucleic Acids Research·Susan TweedieUNKNOWN FlyBase Consortium
Oct 30, 2008·Nucleic Acids Research·Daniel BarrellRolf Apweiler
Nov 26, 2008·Genome Research·Albert J VilellaEwan Birney
Jan 16, 2009·BMC Genomics·Damian SmedleyArek Kasprzyk
May 12, 2009·BMC Bioinformatics·Eric JainElisabeth Gasteiger
Aug 8, 2009·Proteomics·Juan Antonio VizcaínoLennart Martens
Oct 24, 2009·Nucleic Acids Research·B ArandaH Hermjakob
Oct 24, 2009·Nucleic Acids Research·Eli KaminumaYasukazu Nakamura
Oct 28, 2009·Nucleic Acids Research·S VelankarG J Kleywegt
Nov 13, 2009·Nucleic Acids Research·Paul FlicekStephen M J Searle
Nov 13, 2009·Nucleic Acids Research·Rasko LeinonenGuy Cochrane
Nov 17, 2009·Nucleic Acids Research·Dennis A BensonEric W Sayers
Oct 12, 2010·Nucleic Acids Research·Ruth L SealElspeth A Bruford
Nov 6, 2010·Nucleic Acids Research·Judith A BlakeUNKNOWN Mouse Genome Database Group

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Nov 22, 2011·Journal of Computer-aided Molecular Design·Aldo Segura-CabreraMario A Rodríguez-Pérez
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Nov 26, 2013·European Journal of Cell Biology·Bo Xue, Robert C Robinson
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Aug 28, 2012·Bioinformatics·Narendra Kumar, Jeffrey Skolnick
Mar 22, 2012·Database : the Journal of Biological Databases and Curation·Myra K DerbyshireAron Marchler-Bauer
Feb 4, 2012·Database : the Journal of Biological Databases and Curation·Sarah BurgeSarah Hunter
Mar 22, 2012·Database : the Journal of Biological Databases and Curation·Julie ParkEurie L Hong
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Methods Mentioned

surface plasmon resonance

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