Unique characteristics of pyogenic liver abscesses of biliary origin

Surgery
Shaohua ShiShusen Zheng

Abstract

Pyrogenic liver abscesses (PLA) can be caused by cholangitis associated with hepatolithiasis and cholangitis related to an abnormal bilioenteric communication, such as a hepaticojejunostomy or the presence of indwelling biliary stents. Our aim was to evaluate the clinical characteristics of PLA of biliary origin. We compared patients with PLA related to biliary tract disease (PLA-B; n = 125) with patients with PLA not related to biliary tract disease (PLA-NB; n = 444). We also separated the patients with PLA-B into PLA related to biliary tract disease that involved an abnormal bilioenteric communication, including hepaticojejunostomy and indwelling biliary stents (PLA-B-AC; n = 38), and PLA-B not related to abnormal communication (n = 87), and compared them. Among the 569 patients with PLA from 2008 to 2013, the most common etiologies were cryptogenic (n = 341; 60%) and biliary (n = 125; 22%). Patients with PLA-B tended to have a higher maximum body temperature and a greater leukocytosis. The incidences of bacteremia, septic shock, death, and postdischarge recurrence were greater in the PLA-B group when compared with the PLA-NB group. The most commonly isolated pathogenic bacteria in PLA-B group were Escherichia coli (36%) and ...Continue Reading

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Citations

Oct 30, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Shao-Hua ShiShu-Sen Zheng
Jun 10, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Emmanuel LafontAgnès Lefort
Feb 6, 2017·Infectious Diseases and Therapy·Kenneth V I Rolston
Nov 18, 2020·World Journal of Hepatology·Juanita Pérez-EscobarAldo Torre

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