PMID: 29465393Feb 22, 2018Paper

Unique natural exopolysaccharides for biomimetic protective effect against urban pollution

Journal of Cosmetic Science
Magali BorelEstelle Loing

Abstract

Through natural selection, living organisms have evolved well-adapted survival strategies over time. The shallow salt waters of Moorea lagoon are the site of accumulation of microbial mats called "Kopara," in the native Polynesian language. This unique ecosystem is rich in film-forming exopolysaccharides (EPSs) secreted by microorganisms within the biofilm, as a mean to protect themselves from environmental stress (strong ultraviolet [UV], pH, salinity … ). Using blue biotechnology, a manufacturing process was developed to obtain an EPS with skin benefits. The active ingredient (EPS-229) protects against urban pollution, including free radicals, heavy metals, hydrocarbons, and PM2.5(particulate matter with a size lower than 2.5 μm). The anti-lipid peroxidation action of EPS-229 was studied in anin vitroUVB-irradiated keratinocyte culture model, using lipophilic fluorescent probe. The chelating properties of EPS-229 were evaluatedin tuboin the presence of cadmium and lead. The protective effect of EPS-229 on pollution-exposed skin explants was investigated through quantification of released malondialdehyde (MDA) and histological observation of skin morphology using optical microscopy. Clinical evaluation of the protective and cl...Continue Reading

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Related Papers

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Eric F BernsteinSergey M Ksenzenko
Journal of Photochemistry and Photobiology. B, Biology
Estibalitz FernándezLuisa Coderch
© 2022 Meta ULC. All rights reserved