Universal screening and decolonization for control of MRSA in nursing homes: a cluster randomized controlled study

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Cristina BelliniGiorgio Zanetti

Abstract

The risk of carrying methicillin-resistant Staphylococcus aureus (MRSA) is higher among nursing home (NH) residents than in the general population. However, control strategies are not clearly defined in this setting. In this study, we compared the impact of standard precautions either alone (control) or combined with screening of residents and decolonization of carriers (intervention) to control MRSA in NHs. Cluster randomized controlled trial. NHs of the state of Vaud, Switzerland. Of 157 total NHs in Vaud, 104 (67%) participated in the study. Standard precautions were enforced in all participating NHs, and residents underwent MRSA screening at baseline and 12 months thereafter. All carriers identified in intervention NHs, either at study entry or among newly admitted residents, underwent topical decolonization combined with environmental disinfection, except in cases of MRSA infection, MRSA bacteriuria, or deep skin ulcers. NHs were randomly allocated to a control group (51 NHs, 2,412 residents) or an intervention group (53 NHs, 2,338 residents). Characteristics of NHs and residents were similar in both groups. The mean screening rates were 86% (range, 27%-100%) in control NHs and 87% (20%-100%) in intervention NHs. Prevalenc...Continue Reading

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Citations

Dec 15, 2015·Expert Review of Anti-infective Therapy·Maddalena GiannellaPierluigi Viale
Apr 26, 2016·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Deverick J AndersonDaniel J Morgan
Jun 17, 2016·Current Opinion in Infectious Diseases·Morgan J Katz, Mary-Claire Roghmann
Jul 25, 2018·Antimicrobial Resistance and Infection Control·Philipp KohlerAndreas Kronenberg
Jan 12, 2021·Aging Clinical and Experimental Research·M TinelliUNKNOWN ESCMID Study Group for Infections in the Elderly
Dec 12, 2020·Infectious Disease Clinics of North America·Sima L ShararaSara E Cosgrove
Apr 26, 2021·Geriatric Nursing·Eun-Young NohYeon-Hwan Park

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