Unmyelinated tactile afferents underpin detection of low-force monofilaments

Muscle & Nerve
Jonathan ColeHåkan Olausson

Abstract

Human hairy but not glabrous skin has unmyelinated (C) tactile (CT) afferents that project to insular cortex. We studied two subjects with the rare sensory neuronopathy syndrome who lack A-beta fibers but have relatively preserved C-fiber function. Weak monofilaments were detected on hairy skin alone. Hence, the ability to detect light touch does not depend entirely on the A-beta somatosensory system; CT afferents may contribute to the detection of weak monofilaments.

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Citations

Jun 25, 2008·Experimental Brain Research·Helena Backlund WaslingHåkan Olausson
Sep 23, 2009·Experimental Brain Research·India MorrisonHåkan Olausson
Jun 16, 2009·Evidence-based Complementary and Alternative Medicine : ECAM·Thomas LundebergJan Näslund
Jul 6, 2011·The Journal of Physiology·Saad S NagiDavid A Mahns
Apr 9, 2013·The Journal of Pain : Official Journal of the American Pain Society·Saad S Nagi, David A Mahns
Oct 9, 2012·Neurophysiologie clinique = Clinical neurophysiology·L Garcia-Larrea
Oct 28, 2008·Neuroscience and Biobehavioral Reviews·Håkan OlaussonAke Vallbo
Apr 9, 2008·Neuroscience Letters·Håkan W OlaussonM Catherine Bushnell
Dec 17, 2008·Human Brain Mapping·Keri S TaylorKaren D Davis
May 13, 2014·Annals of Neurology·Flavia ManciniGian Domenico Iannetti
Mar 28, 2006·Brain Research·Prisca StennekenGisa Aschersleben
May 21, 2015·Experimental Brain Research·N YousifJ Diedrichsen
May 24, 2014·Neuron·Francis McGloneHåkan Olausson
Jan 1, 2014·Ageing Research Reviews·Johanna DecorpsBerengere Fromy
Mar 19, 2014·Frontiers in Behavioral Neuroscience·Jaquette Liljencrantz, Håkan Olausson
Jan 8, 2013·Pain·Jaquette LiljencrantzHåkan Olausson
Mar 7, 2017·European Journal of Pain : EJP·J LiljencrantzH Olausson
Feb 1, 2007·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Anthony Campbell
Sep 11, 2013·Nature Reviews. Neurology·Andrea TruiniGiorgio Cruccu
Dec 25, 2019·ELife·Andrew G MarshallFrancis P McGlone
Jul 10, 2019·Science Advances·Saad S NagiHåkan Olausson
Sep 24, 2020·Journal of Neurophysiology·Giulia Corniani, Hannes P Saal

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