Unraveling Anthocyanin Bioavailability for Human Health

Annual Review of Food Science and Technology
Mary Ann LilaWilhelmina Kalt

Abstract

This review considers the bioavailability of health-protective anthocyanin pigments from foods, in light of the multiple molecular structures and complicated traffic patterns taken by anthocyanins both as flavonoid metabolites and as phenolic acid metabolites within the body. Anthocyanins have generally been considered to have notoriously poor bioavailability, based on the very low levels typically detected in routine human blood draws after ingestion. Although some investigations have assessed anthocyanin bioavailability solely based on the measurement of parent anthocyanins or phenolic acid breakdown products, more recent research has increasingly revealed the presence, qualitative diversity, relatively high concentrations, and tenacity of molecular intermediates of anthocyanins that retain the unique flavonoid C6-C3-C6 backbone structure. We argue that the persistence of anthocyanin metabolites suggests enterohepatic recycling, leading to prolonged residence time, and supports the notion that anthocyanins are far more bioavailable than previously suggested.

References

Jun 13, 2000·Critical Reviews in Food Science and Nutrition·F Delgado-VargasO Paredes-López
Nov 4, 2000·Gastrointestinal Endoscopy·J E MarkowitzC A Liacouras
Feb 28, 2001·Fresenius' Journal of Analytical Chemistry·M MurkovicW Pfannhauser
Mar 7, 2002·Journal of Biotechnology·Xavier VitracJean-Michel Mérillon
Apr 17, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·V M BreinholtT Friedberg
Aug 15, 2002·Biochemical and Biophysical Research Communications·Sabina PassamontiFulvio Mattivi
May 6, 2003·The Journal of Nutrition·Catherine FelginesChristian Rémésy
Jun 5, 2003·FEBS Letters·Sabina PassamontiFulvio Mattivi
Oct 17, 2003·Phytochemistry·Jin-Ming KongR Brouillard
Dec 4, 2003·The Journal of Nutrition·Séverine TalavéraChristian Rémésy
Mar 5, 2004·Journal of Agricultural and Food Chemistry·Gad G YousefMary Ann Lila
Dec 4, 2004·Journal of Biomedicine & Biotechnology·Mary Ann Lila
Apr 14, 2005·Journal of Agricultural and Food Chemistry·Jian HeM Monica Giusti
Apr 20, 2005·Journal of Mass Spectrometry : JMS·Qizhi HuR Graham Cooks
May 4, 2005·The Journal of Nutrition·Mary Ann LilaConnie M Weaver
May 12, 2005·Journal of Agricultural and Food Chemistry·Séverine TalavéraChristian Rémésy
Aug 2, 2005·Nutritional Neuroscience·Cristina Andres-LacuevaJames A Joseph
Aug 4, 2005·Journal of Agricultural and Food Chemistry·Anne C KurilichJanet A Novotny
Sep 1, 2005·Journal of Agricultural and Food Chemistry·Takashi IchiyanagiTetsuya Konishi
Sep 30, 2005·Journal of Agricultural and Food Chemistry·Catherine FelginesChristian Remesy
Jan 31, 2006·The British Journal of Nutrition·Manal Abd El MohsenJeremy P E Spencer
Mar 21, 2006·Molecular Nutrition & Food Research·Kathrin KahleElke Richling
Apr 26, 2006·Experimental Eye Research·Hitoshi MatsumotoHiroshi Ohguro
May 25, 2006·Journal of Agricultural and Food Chemistry·Xianli WuRonald L Prior
May 30, 2007·Molecular Nutrition & Food Research·Tony K McGhie, Michaela C Walton
Sep 25, 2007·Journal of Medicinal Food·Sun-Hwa KwonKun-Young Park
Jan 24, 2008·Journal of Agricultural and Food Chemistry·Ronald L PriorLuke R Howard
Jan 24, 2008·Journal of Agricultural and Food Chemistry·Wilhelmina KaltPaul E Milbury
Jul 23, 2008·Molecular Nutrition & Food Research·Catherine FelginesFabio Galvano
Sep 26, 2008·Journal of Agricultural and Food Chemistry·Indika EdirisingheTissa Kappagoda
Jun 1, 2006·Nutrition Research Reviews·Colin D Kay
Mar 24, 2009·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Mary H GraceMary Ann Lila
Apr 14, 2009·Cancer Chemotherapy and Pharmacology·Timothy H MarczyloAndreas J Gescher
Dec 18, 2009·Journal of Agricultural and Food Chemistry·William MullenAlan Crozier
Feb 5, 2010·Journal of Agricultural and Food Chemistry·Paul E Milbury, Wilhelmina Kalt

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Citations

Jun 4, 2016·Journal of Agricultural and Food Chemistry·Amandeep K SandhuBritt Burton-Freeman
Jun 17, 2016·Molecular Nutrition & Food Research·Cláudia MarquesAna Faria
Aug 26, 2016·Molecular Nutrition & Food Research·Brett Ronald CutlerPon Velayutham Anandh Babu
Oct 27, 2016·British Journal of Pharmacology·Bo-Wen LinYing-Yu Cui
Feb 14, 2017·Journal of Agricultural and Food Chemistry·David Bars-CortinaMaria José Motilva
May 16, 2017·BioFactors·Giovana JamarLuciana Pellegrini Pisani
Dec 6, 2016·Journal of Food Science·Gary DobsonReijo O Karjalainen
Oct 6, 2017·Food & Function·Di XiaoBritt M Burton-Freeman
Mar 3, 2019·International Journal of Molecular Sciences·Teodora CosteaMaria-Magdalena Mocanu
Jan 12, 2019·Annual Review of Food Science and Technology·David C NiemanNicholas D Gillitt
Jun 12, 2019·International Journal of Molecular Sciences·Masahiro NagaokaKeiko Suzuki
Jul 3, 2019·Nutrients·Bogdan Nicolae ManolescuIleana C Farcasanu
Sep 16, 2018·Microbial Cell Factories·Jian ZhaMattheos A G Koffas
Nov 14, 2019·Critical Reviews in Food Science and Nutrition·Vidmantas BendokasJulius Liobikas
Jan 30, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Michael KaiserAndreas Schieber
Nov 13, 2018·Current Medicinal Chemistry·Antonio SpecialeMariateresa Cristani
May 20, 2020·Journal of Clinical Medicine·Michał CiebieraAyman Al-Hendy
Aug 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Roberto MattioliPaula Silva
Dec 1, 2017·Critical Reviews in Analytical Chemistry·Julia MartínAgustin G Asuero
Nov 15, 2018·Nutrients·Christiane SchönBernd Bonnländer
Apr 8, 2020·Oxidative Medicine and Cellular Longevity·Ricardo Raúl Robles-RiveraAdolfo Daniel Rodríguez-Carrizalez
Aug 6, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Danielly C Ferraz da CostaEliane Fialho
Feb 29, 2020·European Journal of Nutrition·Giovana JamarLuciana Pellegrini Pisani
Oct 13, 2017·Molecular Nutrition & Food Research·Divya BharatPon Velayutham Anandh Babu
Oct 28, 2019·British Journal of Pharmacology·Melanie-Jayne R HowesElaine K Perry
Sep 13, 2019·Journal of Diabetes Research·Olvera-Montaño CeciliaRodríguez-Carrizalez Adolfo Daniel
Jul 24, 2020·Pharmaceutical Research·Diana ColoradoNorman Balcazar
May 10, 2018·Anais Da Academia Brasileira De Ciências·Frank H Quina, Erick L Bastos
Oct 22, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xuhuiqun ZhangBritt M Burton-Freeman
Dec 29, 2020·Seminars in Cancer Biology·David Bars-CortinaMaría-Jose Motilva
Jan 27, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rachel HairOck K Chun

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