Unraveling antimicrobial resistance genes and phenotype patterns among Enterococcus faecalis isolated from retail chicken products in Japan

PloS One
Arata HidanoToshiyuki Tsutsui

Abstract

Multidrug-resistant enterococci are considered crucial drivers for the dissemination of antimicrobial resistance determinants within and beyond a genus. These organisms may pass numerous resistance determinants to other harmful pathogens, whose multiple resistances would cause adverse consequences. Therefore, an understanding of the coexistence epidemiology of resistance genes is critical, but such information remains limited. In this study, our first objective was to determine the prevalence of principal resistance phenotypes and genes among Enterococcus faecalis isolated from retail chicken domestic products collected throughout Japan. Subsequent analysis of these data by using an additive Bayesian network (ABN) model revealed the co-appearance patterns of resistance genes and identified the associations between resistance genes and phenotypes. The common phenotypes observed among E. faecalis isolated from the domestic products were the resistances to oxytetracycline (58.4%), dihydrostreptomycin (50.4%), and erythromycin (37.2%), and the gene tet(L) was detected in 46.0% of the isolates. The ABN model identified statistically significant associations between tet(L) and erm(B), tet(L) and ant(6)-Ia, ant(6)-Ia and aph(3')-IIIa,...Continue Reading

References

May 1, 1991·Antimicrobial Agents and Chemotherapy·F BentorchaT Horaud
Mar 18, 2000·Antimicrobial Agents and Chemotherapy·A PortilloC Torres
May 4, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anne O Summers
Dec 6, 2003·The Journal of Antimicrobial Chemotherapy·Ian PhillipsJohn Waddell
Mar 10, 2004·Applied and Environmental Microbiology·Geert HuysJean Swings
Aug 7, 2004·Journal of Clinical Microbiology·Charlene R JacksonJohn B Barrett
Jan 15, 2005·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·E De LeenerF Haesebrouck
Apr 20, 2005·FEMS Microbiology Letters·Marilyn C Roberts
Jun 21, 2005·Emerging Infectious Diseases·Rob J L WillemsMarc J M Bonten
Mar 16, 2006·Trends in Microbiology·Craig Baker-AustinJ V McArthur
Mar 30, 2006·Antimicrobial Agents and Chemotherapy·Corinna Kehrenberg, Stefan Schwarz
Nov 17, 2006·Nature Reviews. Microbiology·Randall S SingerGeorge Maldonado
Jan 24, 2007·PLoS Computational Biology·Art F Y PoonSimon D W Frost
Sep 28, 2007·Avian Pathology : Journal of the W.V.P.A·K CauwertsF Pasmans
Sep 5, 2009·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Shojiro WatanabeNaoki Watanabe
Oct 29, 2010·Proceedings. Biological Sciences·M J DenwoodS W J Reid
Mar 17, 2012·Nature Reviews. Microbiology·Cesar A Arias, Barbara E Murray
Sep 26, 2012·Antimicrobial Agents and Chemotherapy·Takahiro NomuraHaruyoshi Tomita
Oct 10, 2012·Journal of Food Protection·Midori HiroiTakashi Masuda
Oct 19, 2012·Virulence·Brian L Hollenbeck, Louis B Rice
Nov 10, 2012·American Journal of Epidemiology·Fraser I Lewis, Benjamin J J McCormick
Mar 15, 2013·Preventive Veterinary Medicine·Antoinette LudwigFraser I Lewis
Apr 23, 2013·International Journal of Medical Microbiology : IJMM·Guido WernerKeith Weaver
May 21, 2013·Emerging Themes in Epidemiology·Fraser I Lewis, Michael P Ward
Nov 21, 2013·The Lancet Infectious Diseases·Ramanan LaxminarayanOtto Cars
Jun 20, 2014·Current Opinion in Microbiology·Randall S Singer, Jessica Williams-Nguyen

❮ Previous
Next ❯

Citations

Dec 18, 2016·Tropical Animal Health and Production·Emmanuel Ochefije NgbedeJacob Kwada Pajhi Kwaga
Apr 14, 2018·Foodborne Pathogens and Disease·Narayan PaudyalMin Yue
Nov 23, 2018·Acta Microbiologica Et Immunologica Hungarica·Asieh TajiMohammad Motamedifar
Mar 17, 2020·Frontiers in Veterinary Science·Gilles KratzerSonja Hartnack
Jun 12, 2020·Transboundary and Emerging Diseases·Claire GuinatMathilde C Paul
Oct 7, 2020·The Journal of Antimicrobial Chemotherapy·Stacey S ChernyUri Obolski
Mar 22, 2018·Preventive Veterinary Medicine·Kelson ZawackYrjö T Gröhn
Mar 23, 2021·Journal of Medical Microbiology·Aleksandra TrościańczykBeata Chudzik-Rząd
Apr 15, 2021·PloS One·Gayatri Shankar ChilambiDaria Van Tyne
Jul 24, 2021·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Yeong Bin KimYoung Ju Lee
Aug 22, 2021·Irish Veterinary Journal·Teresa Semedo-LemsaddekManuela Oliveira

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Software Mentioned

JAGS
R

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.