Abstract
Over the last few decades, the prevalence of metabolic syndrome (MetS) has gradually increased. As we know, many prior studies have connected MetS with diabetes, coronary heart disease, and cardiovascular disease. Abdominal aortic calcification (AAC) is a good marker of morbidity and mortality of vascular disease, as its degree may be associated with the severity of coronary artery calcification and disease. The aim of this article is to investigate the connection between MetS and AAC. This retrospective observational study included 2731 participants aged 58 years from the National Health and Nutrition Examination Survey (NHANES) (2013-2014). We used Dual-Energy X-ray Absorptiometry to define the degree of AAC. We defined MetS according to the National Cholesterol Education Program Adult Treatment Panel III definition. A total of 2731 participants with complete data were included for data analysis. In the fully adjusted model, an increase in the severity of AAC with the number of MetS components was still significant with βvalues of AAC Total 24 Score 0.498 (95% confidence interval (CI): 0.018,0.978), 1.016 (95% CI: 0.514,1.519) and 1.426 (95% CI: 0.916,1.937) respectively in 2, 3 and ≧ 4 components. Additionally, associations ...Continue Reading
References
Nov 1, 1995·Arteriosclerosis, Thrombosis, and Vascular Biology·G W CockerillP J Barter
Jun 20, 1998·Arteriosclerosis, Thrombosis, and Vascular Biology·J R NoferG Assmann
Mar 21, 2001·Circulation·P W WilsonL A Cupples
Apr 24, 2001·Diabetes Care·B IsomaaL Groop
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Oct 5, 2002·Circulation Research·Farhad ParhamiLinda L Demer
Nov 12, 2002·Arteriosclerosis, Thrombosis, and Vascular Biology·Hiroshi AzumiMitsuhiro Yokoyama
Apr 23, 2003·Hypertension·Josep RedónGuillermo T Sáez
Feb 27, 2004·European Heart Journal·Jobien K OlijhoekUNKNOWN SMART Study Group
Aug 25, 2004·Circulation·Shaista MalikG Rhys Williams
Oct 9, 2004·The Journal of Clinical Endocrinology and Metabolism·Boris HanselAnatol Kontush
Dec 29, 2005·Diabetes·Ana FortuñoGuillermo Zalba
Oct 24, 2007·Diabetes Research and Clinical Practice·Giancarlo De MattiaSusanna Morano
Nov 4, 2008·Diabetologia·S MoebusUNKNOWN Heinz Nixdorf Recall Study Group
Feb 24, 2010·Hypertension·Nicole E JenskyMatthew A Allison
Mar 29, 2011·Acta Physiologica·M Tesauro, C Cardillo
Jul 26, 2012·Experimental Diabetes Research·Rebecca Hutcheson, Petra Rocic
Jun 18, 2014·Cardiovascular Research·Anatol Kontush
Dec 2, 2014·Trends in Cardiovascular Medicine·Jane A Leopold
Jan 30, 2015·Clinics·Seyma YildizCuneyt Kocas
Sep 6, 2015·Diabetic Medicine : a Journal of the British Diabetic Association·R KatzK Nasir
Jun 30, 2016·Obesity·Mingxia YuanBarry I Freedman
Jul 28, 2016·Current Vascular Pharmacology·Sarmad SaidThomas F Whayne
Oct 7, 2016·Annals of Saudi Medicine·Young-Mi EunSang-Wook Song
Mar 17, 2017·Preventing Chronic Disease·Justin Xavier MooreTomi Akinyemiju
Apr 6, 2017·Diabetologia·Matthew J GurkaMark D DeBoer
Nov 9, 2017·JAMA Cardiology·Shaista MalikNathan D Wong
Nov 8, 2018·BioMed Research International·Hyun Jun KimMin Cheol Joo