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Unrelated donor marrow transplantation for severe aplastic anaemia

Transfusion Science

Dec 10, 1990

M R Howard

Abstract

Severe aplastic anaemia (SAA) is frequently a lethal disease. Allogeneic marrow transplantation may offer the best chance of a cure but more than 50% of eligible patients will lack a suitable family donor. The development of large volunteer registries has established unrelated donor mar...read more

Mentioned in this Paper

Aplastic Anemia
Decreased Immunologic Activity [PE]
HLA Compatibility Testing
Graft-vs-Host Disease
HLA Antigens
Graft-Versus-Host Disease Pathway
Therapeutic Immunosuppression
Graft Rejection
HLA Typing
Hypoplastic Anemia
Paper Details
References
  • References16
  • Citations5
12
  • References16
  • Citations5
1

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Unrelated donor marrow transplantation for severe aplastic anaemia

Transfusion Science

Dec 10, 1990

M R Howard

PMID: 10149542

DOI: 10.1016/0955-3886(91)90118-m

Abstract

Severe aplastic anaemia (SAA) is frequently a lethal disease. Allogeneic marrow transplantation may offer the best chance of a cure but more than 50% of eligible patients will lack a suitable family donor. The development of large volunteer registries has established unrelated donor mar...read more

Mentioned in this Paper

Aplastic Anemia
Decreased Immunologic Activity [PE]
HLA Compatibility Testing
Graft-vs-Host Disease
HLA Antigens
Graft-Versus-Host Disease Pathway
Therapeutic Immunosuppression
Graft Rejection
HLA Typing
Hypoplastic Anemia

Similar Papers Found In These Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Immune Tolerance

Immune tolerance happens when the immune system is not responsive to a substance or organism and does not elicit an immune response. This is a normal physiological response for some antigens, especially when detecting self from non-self. This has been a potential area of therapy for some disorders. Here is the latest research on immune tolerance.

Related Papers

Lancet

Treatment of aplastic anaemia: first do no harm

LancetNovember 15, 2000
J C Marsh
Paper Details
References
  • References16
  • Citations5
12
  • References16
  • Citations5
1
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