PMID: 8943124Nov 1, 1996Paper

Unresectable hepatic tumors in childhood and the role of liver transplantation

Journal of Pediatric Surgery
O A AchilleosJ A Buckels

Abstract

Liver transplantation has been performed in five children with unresectable hepatic tumors who did not have extrahepatic metastases at the time of surgery. Two of the children had hepatoblastomas, one had an infantile hemangioendothelioma, and two had a hepatoma. The two children who had hepatoblastoma are well (37 and 25 months posttransplant) and have no evidence of recurrence. The child with infantile hemangioendothelioma had a successful operation, with good quality of life, but died of tumor recurrence 41 months after transplantation. Both children with hepatomas died, one of graft failure owing to chronic rejection and the other of tumor recurrence 5 months posttransplant. These results suggest that liver transplantation may be successful in children with unresectable hepatic tumors without extrahepatic spread and should be considered particularly for the treatment of hepatoblastoma.

References

Feb 1, 1992·Transplantation·C E HaugA B Cosimi
Aug 1, 1992·Journal of Pediatric Surgery·M ReynoldsA Glicksman
May 28, 1992·The New England Journal of Medicine·R A EzekowitzJ Folkman
Feb 1, 1991·Annals of Surgery·B KoneruT E Starzl
Jan 1, 1991·The Journal of Pediatrics·C W WhiteA Yu
Sep 1, 1990·The British Journal of Surgery·T IsmailP McMaster
May 1, 1986·Journal of Pediatric Surgery·F GauthierC Kalifa
Jan 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T C WuM M Hu
Apr 1, 1988·Annals of Surgery·J G O'GradyR Williams
Jan 1, 1989·Journal of Pediatric Surgery·A PierroM L Greenberg
May 4, 1989·The New England Journal of Medicine·C W WhiteL L Fan
May 1, 1988·Journal of Pediatric Surgery·W J ChenW T Hung
Dec 21, 1988·Journal of the National Cancer Institute·J E GarberT Gedde-Dahl
Oct 1, 1985·Annals of Surgery·S IwatsukiT E Starzl
Oct 1, 1988·Annals of Surgery·S Iwatsuki, T E Starzl
Jan 1, 1986·Journal of Pediatric Surgery·R C Cohen, N A Myers
Jan 1, 1986·Journal of Hepatology·D ClementsP McMaster
Aug 17, 1967·The New England Journal of Medicine·A A deLorimierE Carlsson
May 1, 1973·Archives of Surgery·N M Matolo, D G Johnson
May 15, 1980·Cancer
Dec 1, 1980·American Journal of Clinical Pathology·T ShimodaY Fujii
Jun 1, 1983·AJR. American Journal of Roentgenology·A H DachmanD S Hartman
Oct 1, 1982·Journal of Pediatric Surgery·L NguyenC Stephens
Jan 1, 1995·Journal of Pediatric Surgery·M DavenportE R Howard
Feb 1, 1995·Journal of Pediatric Surgery·M S O'ReillyJ Folkman
Jul 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R PichlmayrB Ringe
Jan 1, 1993·Journal of Surgical Oncology. Supplement·R PazdurA Cangir
Jan 1, 1993·Journal of Surgical Oncology. Supplement·D H Van ThielT E Starzl
Jun 1, 1993·Journal of Hepatology·R Pichlmayer

❮ Previous
Next ❯

Citations

Aug 22, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Joel A RodriguezThomas A Aloia
Jan 12, 2011·Journal of Gastrointestinal Cancer·Merten HommannUtz Settmacher
Aug 2, 2003·Journal of Pediatric Surgery·S WarmannJ Fuchs
Aug 31, 1999·Journal of Pediatric Surgery·W Al-QabandiD Kelly
Mar 4, 2000·Journal of Pediatric Gastroenterology and Nutrition·D A GerberJ Reyes
Mar 7, 2002·Current Opinion in Pediatrics·Jeanne P ZengeTheresa R Grover
Dec 31, 2005·Journal of Pediatric Gastroenterology and Nutrition·Matthew R RileyJohn Kemer
Jan 31, 2009·Srpski arhiv za celokupno lekarstvo·Nada KrstovskiDragan Vukanić
Aug 12, 2003·Cancer·J Marco SchnaterDaniël C Aronson
Dec 27, 2005·Clinics in Liver Disease·Greg Tiao, Frederick C Ryckman
Nov 11, 2008·Pediatric Transplantation·Enke GrabhornRainer Ganschow
Apr 14, 2011·Pediatric Blood & Cancer·Abha A GuptaRonald M Grant
Feb 18, 1999·Journal of Pediatric Surgery·J A DallerJ Reyes
Mar 10, 2001·Clinics in Liver Disease·S V McDiarmid
Feb 24, 2001·Clinics in Liver Disease·J T Stocker
Dec 16, 2004·Pediatric Transplantation·Sukru Emre, Greg J McKenna
Oct 27, 2004·Pediatric Blood & Cancer·Ali BayAli Kaya
Jun 18, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Howard M KatzensteinLaura C Bowman
Feb 5, 2000·Medical and Pediatric Oncology·N A Dower, L J Smith
Sep 28, 2002·Transplantation·Parthi SrinivasanNigel David Heaton
Apr 20, 2002·Transplantation·Kalevi J A KairemoMarkku Heikinheimo
Sep 14, 2002·Medical and Pediatric Oncology·Andrzej ProkuratPawel Rajszys
Nov 24, 2019·European Journal of Pediatrics·Nikolaos ZavrasGeorge Vaos
Aug 14, 1998·Journal of Pediatric Gastroenterology and Nutrition·D A Kelly
Feb 24, 2007·Annals of the Royal College of Surgeons of England·Mark D Stringer
Mar 17, 2004·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Pablo A BejaranoAndreas Tzakis
Aug 1, 2015·World Journal of Gastroenterology : WJG·Liliana ChioreanChristoph F Dietrich
Feb 16, 1999·Seminars in Surgical Oncology·M Reynolds
Aug 13, 2011·Journal of Pediatric Gastroenterology and Nutrition·Oanez AckermannOlivier Bernard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.