Unsedated In-office Transgastrostomy Esophagoscopy to Monitor Therapy in Pediatric Esophageal Disease.

Journal of Pediatric Gastroenterology and Nutrition
Caroline H T HallJoel A Friedlander

Abstract

Monitoring therapy in esophageal inflammatory disorders such as eosinophilic esophagitis and reflux esophagitis often requires frequent endoscopic evaluation. We recently reported the effective use of unsedated in-office transnasal esophagoscopy that significantly decreased costs and anesthetic exposure associated with pediatric esophagoscopy in eosinophilic esophagitis. Here we report a series of pediatric patients with esophagitis with gastrostomy tubes who underwent unsedated transgastrostomy esophagoscopy (TGE) in an office setting. Nine patients (ages 16 months-21 years) tolerated TGE without significant adverse events. Biopsy specimens were adequate for evaluation. This series confirms that unsedated in-office TGE can be used to successfully obtain mucosal biopsies to monitor esophageal inflammatory conditions in children without the use of sedation.

References

Oct 24, 2006·Anesthesia and Analgesia·John C SandersJames P Kelly
Jan 31, 2009·Journal of Pediatric Gastroenterology and Nutrition·Scott PentiukMarc E Rothenberg
Jan 28, 2014·Biomedical Optics Express·Nima TabatabaeiGuillermo J Tearney
Jul 6, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·David A KatzkaRebecca C Fitzgerald
Jan 4, 2015·Contemporary Clinical Trials·Stephen J GleichDavid O Warner
Jul 6, 2015·Gastrointestinal Endoscopy·Joel A FriedlanderJeremy D Prager
Oct 2, 2015·Journal of Gastroenterology and Hepatology·H PhilpottP R Gibson
Nov 21, 2015·Gastroenterology·Ekaterina SafroneevaUNKNOWN International Eosinophilic Esophagitis Activity Index Study Group

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Citations

Jan 22, 2019·Journal of Pediatric Gastroenterology and Nutrition·Lindsey GumerJoel A Friedlander
May 16, 2018·Journal of Pediatric Gastroenterology and Nutrition·Buford Nichols, William J Klish
May 16, 2018·Journal of Pediatric Gastroenterology and Nutrition·Amy Hui-Mei Lin
Apr 26, 2019·Journal of Pediatric Gastroenterology and Nutrition·Lindsey GumerJoel A Friedlander

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