Unstable angina: the significance of ST segment elevation or depression in patients without evidence of increased myocardial oxygen demand

American Heart Journal
S SclarovskyJ Agmon

Abstract

We evaluated 46 patients with unstable angina (UA), who showed no significant changes in heart rate, blood pressure, and double product (as evidence of increased oxygen demand) during episodes of chest pain. Coronary angiography was performed in all patients during the same hospitalization. Of 26 patients with UA and ST depression (group A), 10 had left main coronary artery disease (CAD) and eight had left main equivalent CAD. Of 20 patients with UA and ST elevation (group B), only one had left main CAD and one had left main equivalent CAD. All patients in group A had ST depression in leads V4 and V5, and all patients in group B had ST elevation in leads V2 and V3. The presence of ST depression in leads V4 and V5 in UA patients without evidence of increased oxygen demand may be suggestive of significant left main or left main equivalent CAD. Therefore, coronary angiography is recommended during the same hospitalization.

Citations

Mar 1, 1997·Progress in Cardiovascular Diseases·P R Liebson, L W Klein
Jul 27, 2002·Journal of the American College of Cardiology·Samuel SclarovskyNikus Kjell
Mar 20, 2001·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·S SavonittoR M Califf
Apr 30, 2009·Revista española de cardiología·Samuel Sclarovsky, Javier García-Niebla
Dec 17, 2008·Journal of Electrocardiology·Samuel Sclarovsky
Jul 13, 2004·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Kjell C NikusSamuel Sclarovsky
Jul 21, 2009·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Jørgen Tobias Kühl, Ronan M G Berg
Jul 1, 1989·Clinical Cardiology·T W von DohlenM J Frank
Nov 1, 1990·Annals of Emergency Medicine·T P AufderheideK C Preuss
Jun 1, 1994·American Heart Journal·Y BirnbaumB Strsber
Aug 1, 1989·Circulation·E Braunwald

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