PMID: 2497823Apr 1, 1989Paper

Untreated asymptomatic bacteriuria in girls: II--Effect of phenoxymethylpenicillin and erythromycin given for intercurrent infections

BMJ : British Medical Journal
S HanssonC Svanborg-Edén

Abstract

To investigate the effects of phenoxymethylpenicillin and erythromycin on urinary isolates from patients with untreated asymptomatic bacteriuria. Retrospective study of subgroup of patients from cohort followed up till the end of 1986. Outpatient clinic for children with urinary tract infections. 51 Girls aged under 15 with untreated asymptomatic bacteriuria. Before 1982 intercurrent infections (mostly tonsillitis or otitis) were treated with phenoxymethylpenicillin; after 1982 erythromycin treatment was preferred. Change of bacterial strain in urinary tract and symptomatic recurrences of disease. Bacteria identified by serotype and electrophoretic type and compared before and after antibiotic treatment. Bacteriuria eradicated and replaced by new strains in most patients treated with phenoxymethylpenicillin, leading to symptomatic recurrences in about 15%. Conversely, patients given erythromycin rarely showed change in bacteriuria and none suffered symptomatic recurrence. In girls with untreated asymptomatic bacteriuria the use of phenoxymethylpenicillin for intercurrent infections may lead to a change of urinary bacteria and leave them at substantial risk of acute pyelonephritis. With erythromycin this risk is small (2/20 cour...Continue Reading

References

Feb 15, 1975·Lancet·D C SavageM I Wilson
Jan 1, 1979·Scandinavian Journal of Infectious Diseases·A Heimdahl, C E Nord
Aug 1, 1977·Journal of Medical Microbiology·G Lidin-JansonK Lincoln
Mar 1, 1975·Acta paediatrica Scandinavica·U JodalK Lincoln
Aug 1, 1985·Infection and Immunity·D A CaugantR K Selander
Feb 1, 1987·Acta Paediatrica Japonica; Overseas Edition·Z LaronY Aurbach
Jul 24, 1965·British Medical Journal·C J Hodson, S Wilson

❮ Previous
Next ❯

Citations

Apr 28, 2004·Archives of Internal Medicine·Barbara W Trautner, Rabih O Darouiche
Apr 1, 1995·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·J MartinellU Jodal
Feb 5, 2013·Current Infectious Disease Reports·Betsy Foxman, Miatta Buxton
Jun 1, 1994·International Journal of Antimicrobial Agents·L E Nicolle
Jul 24, 2002·International Journal of Antimicrobial Agents·Björn WulltCatharina Svanborg
Sep 19, 2003·International Journal of Antimicrobial Agents·Björn Wullt
Oct 6, 2000·The New England Journal of Medicine·L E Nicolle
Jun 9, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Florian M E Wagenlehner, Kurt G Naber
Mar 1, 1991·British Journal of Urology·P A Anderson, A M Rickwood
Jul 1, 1990·Postgraduate Medical Journal·K Farrington, P Sweny
Apr 1, 2007·Indian Journal of Urology : IJU : Journal of the Urological Society of India·R Kapoor, S Agrawal
Jul 26, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rabih O Darouiche, Richard A Hull
Jan 3, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Eliana B M GuidoniJulio Toporovski
Nov 11, 2015·International Journal of Urology : Official Journal of the Japanese Urological Association·Fredrik Sundén, Björn Wullt
Jul 1, 1996·Kidney International·M Linshaw
Nov 1, 2011·International Journal of Antimicrobial Agents·Rolf Beetz, Martin Westenfelder
May 24, 2006·Pediatric Clinics of North America·Steven L Chang, Linda D Shortliffe
Oct 22, 2005·International Journal of Medical Microbiology : IJMM·Göran BergstenCatharina Svanborg
Oct 6, 1997·Infectious Disease Clinics of North America·S HanssonU Jodal
Jul 10, 2003·Infectious Disease Clinics of North America·Lindsay E Nicolle
Jun 8, 2014·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Per Brandström, Sverker Hansson
Apr 23, 2016·Pathogens·Lindsay E Nicolle
Jul 9, 2008·Scandinavian Journal of Infectious Diseases·Nils RodheSigvard Mölstad
Mar 22, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lindsay E NicolleReed Siemieniuk
Jun 11, 2019·PLoS Pathogens·Ines AmbiteCatharina Svanborg
Jan 16, 2018·Investigative and Clinical Urology·Byung Soo KimChang Wook Jeong
Feb 1, 1990·The Journal of Urology·S HanssonC Svanborg-Edén
Sep 22, 1998·Clinical Obstetrics and Gynecology·S Faro, D E Fenner
May 30, 2020·International Journal of Molecular Sciences·Lea DenzerChristian Schwerk
Dec 16, 2020·The Journal of Clinical Investigation·Inès AmbiteCatharina Svanborg
May 25, 2020·Lancet·Kjell Tullus, Nader Shaikh
Sep 1, 1991·Infection and Immunity·P AnderssonC Svanborg
Nov 7, 2015·Microbiology Spectrum·Lindsay E Nicolle
Jun 17, 2021·Nature Reviews. Urology·Ines AmbiteCatharina Svanborg

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.