Unusual axillary metastasis of recurrent nasopharyngeal cancer: A case report

Medicine
Deng-Yu KuoPei-Wei Shueng

Abstract

Nasopharyngeal carcinoma (NPC) has a high propensity of metastasis. The most commonly described sites of distant metastasis are the bones, lungs, and liver, whereas axillary metastasis is seldom reported. We hereby present the case of a 66-year-old man with NPC, cT2N2M0, at diagnosis. He had completed chemoradiotherapy and been disease-free for 7 years. After that period, late recurrence in the form of a solitary axillary lymph node metastasis was detected and confirmed by core-needle biopsy. The lesion was chemoresistant but responded to salvage radiotherapy at a dose of 65 Gy in 21 fractions. Post-radiotherapy positron emission tomography scan showed no evidence of disease. We suggested that long-term follow-up of NPC patients is important because a late relapse may occur at an unusual site. Aggressive management of solitary metastasis may achieve good outcome.

References

Apr 20, 1999·Head & Neck·W M Koch
Dec 24, 2010·European Annals of Otorhinolaryngology, Head and Neck Diseases·Y BensoudaH Errihani
Nov 24, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Deborah F DeLairLee K Tan
May 11, 2015·The Lancet Oncology·Pierre BlanchardUNKNOWN MAC-NPC Collaborative Group

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Citations

Aug 11, 2021·Experimental and Therapeutic Medicine·Cristina Marinela OpreanAna Cristina Bredicean

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Methods Mentioned

BETA
biopsy

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