Jan 1, 1976

Unusual behaviour of a protein: reversible quantitative precipitation of staphylococcal delta-haemolysin by low concentrations of some organic solvents

International Journal of Peptide and Protein Research
N G Heatley

Abstract

Staphylococcal delta-haemolysin is precipitated from watery solutions by low concentrations of chloroform. The effect on this precipitation of pH, kind and concentration of salts, and concentration of, and time of exposure to, chloroform have been investigated. Some but not all of the other solvents tested cause a similar precipitation. The haemolytic activity is not destroyed and under appropriate conditions precipitation is quantitative. The dry lysin will take up nearly double its weight of chloroform when exposed to the vapour. Some is bound strongly.

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Mentioned in this Paper

Sulfates, Inorganic
Bacterial Proteins
Genus staphylococcus
Calcium Chloride, Anhydrous
Vibration - Physical Agent
Sodium Chloride, (24)NaCl
Lysine Hydrochloride
Ammonium Sulfate
Hemolysin
Hydrogen-Ion Concentration

About this Paper

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