Unusual forms of cutaneous leishmaniasis due to Leishmania major

Journal of the European Academy of Dermatology and Venereology : JEADV
M SolomonE Schwartz

Abstract

Cutaneous leishmaniasis (CL) due to Leishmania major (L. major) is common in the Middle East; however, this skin infection may be under-diagnosed when it presents atypically. To highlight the occurrence of uncommon presentations of CL that may elude diagnosis. A retrospective study was performed among patients who presented at The Sheba Medical Center between 2005 and 2014 with atypical clinical presentations of CL due to L. major. Twelve patients with unusual clinical presentations of L. major CL were identified. All infections were acquired in L. major - endemic areas of Israel. The average age was 37 years. The average number of lesions was 2. Nine patients presented with a form that mimicked other forms of CL, such as lupoid, giant ulcer, sporotrichoid and recidivans, and three had a variant resembling other infectious skin diseases, such as erysipeloid and verruciform. All patients required systemic therapy. Cutaneous leishmaniasis due to L. major can masquerade as many other infectious and inflammatory diseases. In addition, it can mimic clinical forms of New World CL. We suggest that in endemic countries or in travellers returning from countries where L. major is endemic, polymerase chain reaction (PCR) for Leishmania-sp...Continue Reading

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Citations

Oct 22, 2016·Emerging Infectious Diseases·Justin S KuilderPerry J J van Genderen
Dec 24, 2019·The Journal of Dermatological Treatment·Alireza FiroozYahya Dowlati
Jul 3, 2019·Journal of Tropical Medicine·Yamuna SiriwardanaNadira D Karunaweera
Dec 22, 2020·Journal of Travel Medicine·Adam DalalEli Schwartz

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