Unusual hematologic disease affecting Caucasian children traveling to Southeast Asia: acquired platelet dysfunction with eosinophilia.

Hematology Reports
Anselm Chi-Wai Lee

Abstract

An 11-year-old American boy was staying with his family in Indonesia. He presented with a 5-month history of recurrent bruises and ecchymosis. A clinical diagnosis of acquired platelet dysfunction with eosinophilia was made when his full blood counts showed hypereosinophilia (7.4×10(9)/L) with normal platelet count and gray platelets under the microscope. The diagnosis was supported by abnormal platelet aggregation tests consistent with a storage pool disorder. The bleeding symptoms and eosinophilia resolved a month later with a full course of antihelminthic therapy. Hematologists should be aware of this unusual disease in travelers returning from the Southeast Asia.

Citations

Jul 14, 2016·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Diksha D YadavRumma V Manchanda
Jul 23, 2013·Life Sciences·Aline Mendes MazieroGilberto De Nucci
Feb 3, 2018·Acta Haematologica·Thirachit ChotsampancharoenEdward McNeil
Aug 30, 2017·Archives of Disease in Childhood. Education and Practice Edition·Guan Hao Tan, Rajat Bhattacharyya
Oct 20, 2018·Journal of Pediatric Hematology/oncology·Anselm Chi-Wai Lee
Jul 30, 2020·Journal of Paediatrics and Child Health

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