Unusual hyperplasia of anogenital mammary-like glands

The American Journal of Dermatopathology
Dmitry V KazakovMichal Michal

Abstract

Anogenital mammary-like glands, although known to exist (as ectopic breast tissue) as early as 1872, have only recently been thoroughly studied and suggested to be the possible origin for various neoplastic (benign and malignant) and reactive conditions that show a striking homology with lesions in the breast. Reported herein is an unusual benign lesion involving anogenital mammary-like glands in the perineal area of a 41-year-old woman. The lesion is unique in that it does not fully fit into any of the previously recognized conditions affecting anogenital mammary-like glands nor has it an apparent well-defined mammary counterpart. Microscopically, at first glance the lesion appeared as a cluster of extended anogenital mammary-like glands of variable complexity and a lobular architecture, which probably resulted from a compact proliferation of closely situated ducts with small, round lumens (when cut transversally). When cut longitudinally, some of these tiny ducts appeared to bud from larger ductal structures, resembling so-called satellitosis in the breast and this gave a fibroadenomatous appearance to the areas. In addition, there were adenosis-like areas. This lesion extends the spectrum of changes seen in anogenital mammar...Continue Reading

References

Dec 1, 1976·Cancer·R L Guerry, H R Pratt-Thomas
Dec 1, 1991·The American Journal of Dermatopathology·S C van der Putte
Mar 1, 1969·The Journal of Obstetrics and Gynaecology of the British Commonwealth·A M Hassim
Aug 1, 1995·Acta Anaesthesiologica Scandinavica·H MitsuhataR Shimizu
Apr 1, 1994·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·S C van der Putte
Sep 1, 1993·Gynecologic Oncology·C L BaileyJ L Powell
Apr 1, 1993·The Anatomical Record·S C Van der Putte
Feb 1, 1996·The American Journal of Dermatopathology·P Donati, A Amantea
Oct 27, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·V ParadisP Bedossa
Mar 30, 1999·Gynecologic Oncology·W P IrvinW A Andersen
Jun 2, 2000·Archives of Gynecology and Obstetrics·G GülerT Küçükali
Feb 24, 2001·The American Journal of Dermatopathology·C Urso, C Anichini
Jul 13, 2001·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·C Y Castro, M Deavers
Jul 27, 2001·International Journal of Surgical Pathology·M T ChuliaF I Aranda
Sep 26, 2002·Archives of Pathology & Laboratory Medicine·Moonja Chung-ParkAbdelwahab Shalodi
Dec 4, 2002·Histopathology·J D SingtonK Hollowood
Jan 15, 2003·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Keiko OshidaMasaru Miyazaki
Aug 1, 1954·American Journal of Clinical Pathology·R A BURGER, P M MARCUSE
Jul 14, 2004·Gynecologic and Obstetric Investigation·C BaykalO F Demir
Sep 14, 2004·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S OhiraI Konishi
Oct 8, 2004·Histopathology·G CollinaM Reggiani
Aug 13, 2005·The American Journal of Surgical Pathology·Dmitry V KazakovMichal Michal
Jan 18, 2006·Journal of Cutaneous Pathology·Renato G Panizzon
Jan 31, 2006·Journal of Cutaneous Pathology·Dmitry V KazakovMichal Michal

❮ Previous
Next ❯

Citations

Feb 26, 2013·The American Journal of Dermatopathology·Anastasia M KonstantinovaDmitry V Kazakov
Dec 29, 2007·Journal of Lower Genital Tract Disease·Clarissa BambaoMichael Shier
May 28, 2010·The American Journal of Surgical Pathology·Maria Teresa Fernandez-FiguerasDmitry V Kazakov
Sep 22, 2007·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Dmitry V KazakovMichal Michal
Sep 25, 2009·Journal of Cutaneous Pathology·Slim CharfiDenis Chatelain
Sep 24, 2016·The American Journal of Dermatopathology·Anastasia M KonstantinovaDmitry V Kazakov
Dec 21, 2010·Advances in Anatomic Pathology·Dmitry V KazakovMichal Michal
Apr 18, 2019·Case Reports in Pathology·Sakinah A ThiryayiDanny Ghazarian
Sep 9, 2020·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Anastasia M KonstantinovaDmitry V Kazakov

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.