Unusual patterns of I-131 contamination

Annals of Nuclear Medicine
Mehmet OzguvenSabri Dundar

Abstract

Whole body imaging with radioiodine can detect functioning metastases, which can often be effectively treated with appropriate amounts of radioiodine. Non-physiologic I-131 uptake detected on images is usually interpreted as suggesting functioning thyroid metastases. However, extra-thyroidal I-131 accumulation does not always imply thyroid cancer metastases and has been reported on many occasions, including various non-thyroidal neoplasms, and contamination by body secretions. In order to avoid unnecessary therapeutic interventions it is extremely important to properly distinguish false-positive sites of I-131 localization. Three patients with unusual radioiodine contamination patterns, either presented for the first time or rarely presented in the existing literature, were reported. Reported cases consist of contamination in hair (due to styling hair with sputum), contamination in neck (due to drooling during sleep) and, contaminated chewing gum. False positive contamination sources were clarified by careful examination of patients and further images when necessary.

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Citations

Nov 25, 2006·Thyroid : Official Journal of the American Thyroid Association·Seyed Rasoul Zakavi, Vahidreza Dabbagh Kakhki
Aug 31, 2012·Radiology and Oncology·Salih Sinan GültekinAhmet Oğuz Hasdemir
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Feb 23, 2010·Clinical Nuclear Medicine·Archi AgrawalRamesh Asopa
Dec 16, 2010·Clinical Nuclear Medicine·Daniel BulzicoRossana Corbo
Mar 22, 2006·Clinical Nuclear Medicine·Chrissa SiokaA Zouboulidis
Apr 4, 2014·International Journal of Endocrinology and Metabolism·Pelin Ozcan KaraAlihan Erdogan
Feb 9, 2012·Clinical Nuclear Medicine·Cina Shin-Loong TongLeung Sing-Fai

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