Unusual response to continuous positive pressure ventilation

European Journal of Intensive Care Medicine
Guillermo A RaimondiM L Marchissio


In a patient with acute respiratory failure due to aspiration pneumonia, PaO2 decrease and Qs/Qt increase were observed during continuous positive pressure ventilation. This paradoxical finding was attributted to vascular collapse in well ventilated upper alveoli associated with blood flow redistribution to dependent hypoventilated areas with low ventilation-perfusion relationships.


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Related Concepts

Diastolic Blood Pressure
Cardiac Output
Positive End-Expiratory Pressure
Pulmonary Circulation
Respiratory Failure
Ventilation-Perfusion Ratio

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