Unusually elevated liver radioactivity on F-18 FDG PET in Hodgkin's disease: hepatic 'superscan'

Clinical Nuclear Medicine
Sandip Basu, N Nair

Abstract

Increased focal concentration of FDG in the background of relatively lower normal hepatocyte uptake is usually regarded as the hallmark of metastatic involvement of the liver from a known primary. The authors present the clinical, radiologic, and laboratory profile of a very unusual hepatic uptake pattern in a case of Hodgkin disease, in which the FDG PET showed intensely diffuse hepatic tracer uptake and was the earliest indicator of extensive hepatic involvement by the disease process. The diagnosis of hepatic involvement with lymphoma was inferred. As experience with FDG PET is growing, it is important to become familiar with the various physiological and pathologic FDG uptake patterns. The term "hepatic superscan", demonstrating intense diffuse hepatic tracer uptake coupled with surprisingly low brain and cardiac FDG uptake, owes its origin from its apparent similarity with the superscan seen in conventional skeletal scintigraphy and represents an entity hitherto undescribed.

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Citations

May 28, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Young Jin JeongChang-Yeol Yim
Sep 9, 2010·Annals of Nuclear Medicine·Kohei HanaokaMitsugu Sumita
Dec 24, 2005·Clinical Nuclear Medicine·Hung-Yi SuShih-Jen Wang
Nov 7, 2009·Clinical Nuclear Medicine·Vladimir TichelaarHiltje de Graaf
Jul 16, 2010·Clinical Nuclear Medicine·Sanjeev Taneja, Dwight M Achong
Jun 1, 2012·Nuclear Medicine and Molecular Imaging·Minyoung OhJin-Sook Ryu
Mar 22, 2018·Clinical Nuclear Medicine·Hongyan YinHongcheng Shi
Jun 13, 2018·Clinical Nuclear Medicine·Zhanli FuQian Li
Jul 24, 2018·Clinical Nuclear Medicine·Xin-Yun ZhangQuan-Yong Luo
Aug 3, 2010·Journal of Korean Medical Science·Dae-Weung KimSei-Hoon Yang
Mar 26, 2014·Clinical Nuclear Medicine·Bulin DuBailing Hsu
May 6, 2020·Clinical Nuclear Medicine·Nilufer YildirimBerrak Gumuskaya

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