Up-regulation of vimentin expression during regeneration in the adult fish brain

Neuroreport
Sorcha C Clint, Günther K H Zupanc

Abstract

In contrast to mammals, the brains of teleost fish exhibit an enormous regenerative capacity following injury. Here, we have examined the potential role of vimentin in this wound healing. Fifteen days after application of a mechanical lesion to the corpus cerebelli in the teleost fish Apteronotus leptoryhnchus, the areal density of vimentin-positive fibres increased significantly at the lesion site and in the remaining ipsilateral molecular layer. This density remained elevated throughout the time period of up to 100 days examined. Based on this spatio-temporal pattern of vimentin up-regulation we propose that this intermediate filament protein is involved in the survival, differentiation, and/or dendritic growth of the new cells that replace damaged cells in the injury zone.

References

Apr 1, 1988·Brain : a Journal of Neurology·B A YaqubH Whitaker
Feb 1, 1981·Experimental Neurology·D DahlA Bignami
Apr 1, 1993·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·D SchifferA Attanasio
Jul 8, 1996·The Journal of Comparative Neurology·G K ZupancG B Rascher
Aug 26, 1998·Experimental Neurology·G K ZupancH Schwarz

❮ Previous
Next ❯

Citations

Feb 8, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·G K H Zupanc
May 12, 2009·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Ruxandra F SîrbulescuGünther K H Zupanc
Mar 27, 2010·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Ruxandra F Sîrbulescu, Günther K H Zupanc
Dec 17, 2002·The Journal of Comparative Neurology·Frederic MercierGlenn I Hatton
Feb 22, 2008·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Eduarda M SantosCharles R Tyler
May 23, 2003·Glia·Günther K H Zupanc, Sorcha C Clint
Mar 6, 2013·Biochimica Et Biophysica Acta·Laura CogliCecilia Bucci
Apr 6, 2021·Frontiers in Cell and Developmental Biology·Jolien Van HouckeLutgarde Arckens

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.