Up-to-date on the HELLP syndrome (Hemolysis, Elevated Liver enzymes and Low Platelets)

La Revue de médecine interne
F Medhioub KaanicheM Bouaziz

Abstract

HELLP syndrome is an acronym for Hemolysis, Elevated Liver enzymes and Low Platelets. It is generally considered in the literature as a particular clinical form of pre-eclampsia, a severe complication of the second half of pregnancy. However, this syndrome can occur in isolation in the absence of pre-eclampsia symptoms. Its pathophysiology remains still unclear. The clinical picture is often incomplete and fruste at first. To date, its diagnosis and management is still the subject of much controversy. Associated or not with a vascular and renal manifestations, the HELLP syndrome is a high-risk maternal disorder. The objective of this article is to review the pathophysiological and clinical data and current treatment.

References

Jun 1, 1985·American Journal of Obstetrics and Gynecology·T J BenedettiV Williams
May 1, 1993·The Australian & New Zealand Journal of Obstetrics & Gynaecology·E F MagannJ N Martin
Mar 5, 1998·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·P Vigil-De Gracia, E García-Cáceres
Dec 10, 1998·European Journal of Obstetrics, Gynecology, and Reproductive Biology·V TsatsarisJ Milliez
May 25, 2001·Critical Care Medicine·J F HazelgroveG B Smith
Jul 10, 2003·Obstetrics and Gynecology·Baha M Sibai
Sep 17, 2004·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·E J WatermanP von Dadelszen
Nov 6, 2004·Seminars in Nephrology·Christopher W G Redman, Ian L Sargent
Mar 8, 2005·Best Practice & Research. Clinical Obstetrics & Gynaecology·Lelia Duley
Apr 14, 2005·Annales Françaises D'anesthèsie Et De Rèanimation·Y Blanloeil, UNKNOWN Société Francaise d'anesthésie et de réanimation
Sep 20, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Wessel GanzevoortUNKNOWN PETRA investigators
Feb 18, 2006·Gynécologie, obstétrique & fertilité·P CollinetF Puech
Apr 25, 2006·American Journal of Obstetrics and Gynecology·James N MartinChristian M Briery
Apr 3, 2007·Obstetrics and Gynecology·Baha M Sibai
Jun 6, 2007·American Journal of Obstetrics and Gynecology·Baha M Sibai, John R Barton
Nov 15, 2008·Gynécologie, obstétrique & fertilité·G BeucherM Dreyfus
Mar 30, 2010·Annales Françaises D'anesthèsie Et De Rèanimation·O CollangeUNKNOWN Société française de anesthésie et de réanimation
Sep 22, 2012·Gynécologie, obstétrique & fertilité·G KayemB Haddad
May 29, 2013·La Revue de médecine interne·M PuyadeO Pourrat

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Citations

Jul 30, 2021·Biochemical Pharmacology·Abdalla M WednMahmoud M El-Mas

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