PMID: 11342794May 9, 2001Paper

Update in podocyte biology

Current Opinion in Nephrology and Hypertension
K EndlichR Witzgall

Abstract

Knowledge of podocyte biology is growing rapidly. Podocytes are crucially involved in most hereditary diseases affecting the glomerulus, which all exhibit podocyte-specific defects, that is, foot process effacement and protein leakage. Efforts to understand molecular mechanisms causing these derangements are increasingly successful and will allow a better targeting of interventions to halt the progression of chronic renal disease.

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