PMID: 9536166Apr 16, 1998Paper

Update of the morbidity experience of employees potentially exposed to chlorpyrifos

Occupational and Environmental Medicine
C J BurnsM K Lee

Abstract

Chlorpyrifos, an organophosphate ingredient of several important insecticides, has been manufactured at The Dow Chemical Company for 25 years. A previous morbidity study among employees of The Dow Chemical Company found no increased prevalence of illness or symptoms among employees potentially exposed to chlorpyrifos from 1977 to 1985 compared with matched controls. The purpose of the current study was to update the original study to 1994, thereby increasing the statistical power. In the present study, 496 potentially exposed subjects were identified and matched for age, race, sex, pay, and year of hire to 911 control subjects. Morbidity data were abstracted from company medical records. The prevalence of peripheral neuropathy was not significantly increased among this group of employees potentially exposed to chlorpyrifos. Significantly increased prevalence odds ratios were identified for five diagnostic categories: diseases of the ear and mastoid process; acute respiratory infections; other diseases of the respiratory system; general symptoms, signs, and ill defined conditions; and symptoms, signs, and ill defined conditions involving the digestive system. There was a strong association of diagnosis with duration of observati...Continue Reading

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Citations

Feb 25, 2006·Occupational and Environmental Medicine·C J BurnsR J Richardson
Oct 13, 2007·American Journal of Respiratory and Critical Care Medicine·Jane A HoppinDale P Sandler
Apr 7, 2000·Environmental Health Perspectives·K SteenlandC Knott
Apr 24, 2007·Environmental Health Perspectives·Won Jin LeeDale P Sandler
Jun 22, 2006·Journal of Occupational Health·Jong ParkSo-Yeon Ryu
Apr 30, 2004·Muscle & Nerve·James W AlbersStanley Berent
Jun 2, 2015·European Respiratory Review : an Official Journal of the European Respiratory Society·Ali MamaneGhislaine Bouvier
Aug 30, 2008·Critical Reviews in Toxicology·David L EatonPeter S Spencer
Feb 20, 2002·Journal of Occupational and Environmental Medicine·Carol J BurnsMonica Chau
Jun 29, 1999·Analytical Chemistry·W M DraperP R Michael

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