Update on Cardiovascular Disease Risk in Patients with Rheumatic Diseases

Rheumatic Diseases Clinics of North America
Rachel H MackeyLarry W Moreland

Abstract

Cardiovascular disease (CVD) risk is 1.5-fold higher in rheumatoid arthritis (RA), partly due to subclinical atherosclerosis that develops before the diagnosis of RA. Dyslipidemia in RA is better quantified by lipoproteins and apolipoproteins than by cholesterol levels. Current risk factors likely underestimate CVD risk by underestimating prior risk factor levels. Some of the 2-fold higher risk of heart failure and total mortality in RA may be due to myocardial disease caused by inflammation. Per recent recommendations, to reduce CVD risk in RA, control disease activity, reduce inflammation, and aggressively treat CVD risk factors.

Citations

Jan 19, 2019·Zeitschrift für Rheumatologie·K Krüger, H Nüßlein
May 31, 2019·Current Opinion in Lipidology·Rachel H MackeyLarry W Moreland
Apr 8, 2020·Rheumatology International·Gizem AyanVedat Hamuryudan
Oct 9, 2019·Nature Medicine·Dawn M FernandezChiara Giannarelli
Sep 15, 2020·Modern Rheumatology·Hiroyuki NakamuraTatsuya Atsumi
Mar 17, 2020·BMC Rheumatology·Alessia AlunnoMaurizio Cutolo
Jul 14, 2020·Frontiers in Immunology·Serena ColafrancescoRoberta Priori
Jul 20, 2019·Joint, Bone, Spine : Revue Du Rhumatisme·Sylvain MathieuMartin Soubrier

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