Update on ischemia-reperfusion injury in lung transplantation

Current Opinion in Organ Transplantation
Fengshi Chen, Hiroshi Date

Abstract

Primary graft failure, which represents one of the most frequent causes of early mortality, is mostly caused by ischemia-reperfusion injury (IRI). IRI may also induce rejection, which is the principal cause of mortality after transplantation. It is essential to understand the mechanism of pulmonary IRI for improving the outcomes of lung transplantation, and therefore we reviewed the state of the art concerning pulmonary IRI in lung transplantation. Numerous strategies have been conducted to reduce IRI after lung transplantation both from the experimental and clinical aspects. The greatest efforts have been done in the method of lung preservation and reperfusion. Recently, ex-vivo lung perfusion system was developed and has been clinically introduced. Furthermore, more experimental studies to understand the pathophysiology of IRI and to alleviate lung IRI have been performed worldwide, and various new treatment modalities including inhalation therapy with therapeutic gases and substances, fibrinolytic treatment, subzero preservation, and mesenchymal stromal cell therapy are going to be applied to the clinical practice. IRI, whose pathophysiology remains incompletely understood, is one of the most critical phenomena in lung trans...Continue Reading

References

Feb 18, 2003·American Journal of Respiratory and Critical Care Medicine·Marc de PerrotShaf Keshavjee
Jan 1, 2005·Yonsei Medical Journal·Fengshi ChenHiromi Wada
Oct 18, 2008·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Toshihiro OkamotoToru Bando
Apr 1, 2010·Seminars in Respiratory and Critical Care Medicine·James C LeeShaf Keshavjee
Apr 15, 2011·The New England Journal of Medicine·Marcelo CypelShaf Keshavjee
Feb 7, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Daisuke NakajimaHiroshi Date
Apr 27, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Jin SakamotoHiroshi Date
Aug 28, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Akihiro OhsumiHiroshi Date
Oct 9, 2012·Seminars in Cardiothoracic and Vascular Anesthesia·Paul D WeykerBrigid C Flynn
Dec 21, 2012·Current Opinion in Organ Transplantation·Naima SouidiMartina Seifert
Mar 12, 2013·American Journal of Physiology. Lung Cellular and Molecular Physiology·Tomohiro KawamuraAtsunori Nakao
Mar 19, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Hideki MotoyamaHiroshi Date
Mar 26, 2013·The Korean Journal of Internal Medicine·Stefan W Ryter, Augustine M K Choi
Jan 1, 2014·The Journal of Surgical Research·Caroline Van De WauwerDirk E M Van Raemdonck
Jan 17, 2014·The Lancet. Respiratory Medicine·Laveena MunshiMarcelo Cypel
Feb 12, 2014·Journal of Cellular Biochemistry·Mariana A AntunesPatricia R M Rocco
Mar 20, 2014·Annals of the American Thoracic Society·Alison BeerMichael Eberlein
Apr 25, 2014·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Jing-Xiang WuMei-Ying Xu
Apr 29, 2014·The Journal of Surgical Research·Nassim FardArianeb Mehrabi
May 16, 2014·Annals of the American Thoracic Society·Joshua M Diamond, Vivek N Ahya
May 23, 2014·Surgery Today·Masaki IkedaHiroshi Date
Jun 10, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M Z AkhtarC W Pugh
Jul 11, 2014·American Journal of Respiratory Cell and Molecular Biology·Pengyu ZhangXin Zhou
Jul 22, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Hideki MotoyamaHiroshi Date
Aug 8, 2014·Transplantation·John Dark
Sep 23, 2014·American Journal of Physiology. Lung Cellular and Molecular Physiology·Shampa ChatterjeeAron B Fisher
Sep 23, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Roger D YusenUNKNOWN International Society for Heart and Lung Transplantation
Nov 29, 2014·Thoracic Surgery Clinics·Marcelo Cypel, Shaf Keshavjee
Dec 3, 2014·Respiratory Physiology & Neurobiology·Hana MrazkovaJan Herget
Dec 9, 2014·American Journal of Respiratory and Critical Care Medicine·David M SayahMark R Looney
Feb 19, 2015·Nature Protocols·Bote G BruinsmaKorkut Uygun
Mar 18, 2015·The Journal of Surgical Research·Tetsu YamadaHiroshi Date

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Citations

Mar 25, 2016·Journal of Translational Medicine·Qifeng ZhaoXingti Hu
Oct 25, 2016·The Annals of Thoracic Surgery·Satona TanakaHiroshi Date
Oct 17, 2016·The Annals of Thoracic Surgery·Keiji OhataHiroshi Date
Mar 23, 2017·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F PaganoG Frati
Aug 20, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Max T BuchkoJayan Nagendran
Mar 21, 2017·Surgery Today·Teruya KomatsuHiroshi Date
Apr 2, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Mamoru TakahashiHiroshi Date
Jul 2, 2018·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Pio ContiTheoharis C Theoharides
Jun 2, 2020·Journal of Anesthesia·Zhaosheng JinDaqing Ma
Nov 5, 2019·The Journal of Thoracic and Cardiovascular Surgery·Toyofumi F Chen-Yoshikawa, Daisuke Nakajima
Feb 4, 2021·The International Journal of Artificial Organs·Katharina KalkaAchim Koch
Feb 23, 2021·The Journal of Thoracic and Cardiovascular Surgery·Satoshi UedaHiroshi Date
Jul 11, 2020·The Annals of Thoracic Surgery·Hidenao KayawakeHiroshi Date
Feb 3, 2019·The Journal of Thoracic and Cardiovascular Surgery·Toyofumi F Chen-Yoshikawa
Jun 4, 2021·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Fumiaki GochiHiroshi Date
Jun 3, 2021·Cells·Toyofumi Fengshi Chen-Yoshikawa
Jul 22, 2020·The Journal of Thoracic and Cardiovascular Surgery·Naoki Ozeki, Toyofumi Fengshi Chen-Yoshikawa
Nov 6, 2018·The Journal of Thoracic and Cardiovascular Surgery·Masao SaitoHiroshi Date
Sep 4, 2019·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·Davide ZampieriFederica Casiraghi

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