Update on latest advances in time-of-flight PET.

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
Suleman Surti, Joel S Karp

Abstract

This paper provides an update on time-of-flight (TOF) PET with a focus on latest hardware developments leading to current commercial PET/CT instruments. We describe advances in scintillator development, new photosensors and associated electronics readout, and detector designs for utilization in complete systems. Next, we introduce the latest commercial PET/CT scanners based on the aforementioned technologies, and discuss the detector design choices made that are relevant to differences in the system performance. Finally, we end with a discussion of the latest performance benchmarks for improved timing in PET detectors, challenges in scaling this performance to a complete system, and the outlook towards achieving a sub-50 ps coincidence timing resolution (CTR) in a PET detector.

Citations

Mar 13, 2021·Physics in Medicine and Biology·Chunhui ZhangZheng Liu
May 16, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Julian M M RogaschCarsten Kobe
Nov 2, 2021·Medical Physics·Neus CucarellaAntonio J Gonzalez

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