Update on mitral repair in dilated cardiomyopathy

Journal of Cardiac Surgery
Matthew A Romano, S F Bolling

Abstract

Heart failure is one of the leading causes of hospitalization worldwide. Mitral regurgitation (MR) is a known complication of end-stage cardiomyopathy and is associated with a poor prognosis due to progressive mitral annular dilation. A vicious cycle of continuing volume overload, ventricular dilation, progression of annular dilation, increased LV wall tension, and worsening of MR and CHF occur. Commonly, these patients were managed medically with diuretics and afterload reduction, and frequently with mitral valve replacement, both of which have poor long term survival in patients with CHF and MR. Over a 10-year period we prospectively studied over 200 patients with cardiomyopathy and severe MR who underwent mitral valve repair utilizing an undersizing overcorrecting annuloplasty ring. The mortality was low with one intraoperative death and eight 30-day mortalities. There were 26 late deaths; 2 of these patients had progression of heart failure and underwent transplantation. The 1-, 2-, and 5-year actuarial survivals have been 82%, 71%, and 52%, respectively. The NYHA class has improved for all patients from a preoperative mean of 3.2 +/- 0.2 to 1.8 +/- 0.4 postoperatively. All patients demonstrated improvement in ejection frac...Continue Reading

Associated Clinical Trials

References

Dec 1, 1992·Journal of the American College of Cardiology·T KonoS Goldstein
Dec 1, 1991·The Annals of Thoracic Surgery·W G HendrenD M Cosgrove
Mar 1, 1990·Journal of the American College of Cardiology·C J PitarysD E Hansen
Nov 1, 1987·The American Journal of Medicine·L W StevensonV Fond
Aug 1, 1987·European Heart Journal·A GallinoM Turina
Apr 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·S F BollingD S Bach
Sep 1, 1994·The Annals of Thoracic Surgery·C W AkinsW G Austen
Aug 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·J M AlvarezC Choong
Jan 1, 1997·European Heart Journal·L Tavazzi
Feb 25, 1998·The Journal of Thoracic and Cardiovascular Surgery·S F BollingD S Bach
Dec 1, 1998·JAMA : the Journal of the American Medical Association·S A Hunt
Dec 19, 1998·Journal of the American College of Cardiology·T AkasakaJ Yoshikawa
Apr 12, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·E S BishayE H Blackstone
Nov 21, 2001·Journal of Cardiac Surgery·D BitranS Silberman
Nov 26, 2002·The Journal of Thoracic and Cardiovascular Surgery·Patrick M McCarthy
Nov 26, 2002·The Journal of Thoracic and Cardiovascular Surgery·Alexandre Ciappina HuebSérgio Almeida de Oliveira

❮ Previous
Next ❯

Citations

Apr 17, 2009·Herz·Matthias PaulEric Schulze-Bahr
Sep 6, 2013·General Thoracic and Cardiovascular Surgery·Kazunori YoshidaYutaka Okita
Nov 27, 2008·Current Heart Failure Reports·Joseph H Gorman, Robert C Gorman
Dec 14, 2011·Current Heart Failure Reports·Juan A Crestanello
Mar 5, 2005·The New England Journal of Medicine·Catherine M Otto, Christopher T Salerno
Mar 27, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Michele De BonisOttavio Alfieri
Nov 18, 2008·Annual Review of Medicine·Susheel Kodali, Allan Schwartz
Sep 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Sak LeeKyung-Jong Yoo
Jan 27, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Kosaku Nishigawa, Kazuo Tanemoto
Sep 17, 2013·The Journal of Thoracic and Cardiovascular Surgery·Morten O JensenSten L Nielsen
Sep 24, 2010·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·B J L Van den BrandenJ A S Van der Heyden
Apr 29, 2010·Current Cardiology Reports·Mir Wasif Ali, Steven F Bolling
Dec 29, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Satoshi KainumaYoshiki Sawa
Jul 3, 2013·The Journal of Thoracic and Cardiovascular Surgery·Philippe B BertrandDavid Verhaert
Aug 18, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Salvatore ScanduraCorrado Tamburino
Jan 29, 2011·The Journal of Thoracic and Cardiovascular Surgery·Michael A AckerSpencer H Kubo
Nov 26, 2009·The Journal of Thoracic and Cardiovascular Surgery·Daniel J DiBardinoLawrence H Cohn
Feb 24, 2009·Current Problems in Cardiology·Mustafa I AhmedLouis J Dell'Italia
May 24, 2008·The Annals of Thoracic Surgery·Mark A WalshPaul F Kantor
Mar 8, 2008·Journal of Cardiac Failure·Mandeep R MehraJames S Gammie
Oct 9, 2007·Current Problems in Cardiology·Aaron S Blom, Michael A Acker
Dec 13, 2006·Seminars in Thoracic and Cardiovascular Surgery·Joseph H Gorman, Robert C Gorman
Mar 28, 2007·Heart Failure Clinics·Jeroen J BaxErnst E van der Wall
Aug 9, 2006·The American Heart Hospital Journal·William E Cohn
Aug 29, 2006·The Journal of Thoracic and Cardiovascular Surgery·Michael A AckerUNKNOWN Acorn Trial Principal Investigators and Study Coordinators
Sep 27, 2005·The Annals of Thoracic Surgery·Ashish S ShahDonald D Glower
Feb 2, 2010·Journal of the American College of Cardiology·Thomas G Di SalvoJohn G Byrne
Jan 3, 2009·Journal of the American College of Cardiology·John R Kapoor
Jul 1, 2011·Journal of the Saudi Heart Association·Hussein S Al-AmriRieda M El Oakley
Dec 4, 2015·BioMed Research International·Giulio AgnettiFrancesco Nicolini
Nov 14, 2012·British Journal of Hospital Medicine·A SharkeyP Braidley
Nov 15, 2018·Journal of Cardiovascular Development and Disease·Marco Cirillo
Nov 19, 2005·Expert Review of Cardiovascular Therapy·Anita PritisanacHelmut Gulbins
Jun 18, 2009·Current Opinion in Cardiology·Mandeep R MehraRoberto M Benitez
Aug 3, 2021·The Journal of Thoracic and Cardiovascular Surgery·Alexander A BresciaUNKNOWN Michigan Mitral Research Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Seminars in Thoracic and Cardiovascular Surgery
Vinay Badhwar, S F Bolling
Congestive Heart Failure
Vinay Badhwar, Steve F Bolling
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
E S BishayE H Blackstone
The Journal of Thoracic and Cardiovascular Surgery
Eugene A Grossi, Gregory A Crooke
© 2021 Meta ULC. All rights reserved