Update on myocarditis

Journal of the American College of Cardiology
Ingrid KindermannMichael Böhm

Abstract

Myocarditis is an inflammatory disease of the heart frequently resulting from viral infections and/or post-viral immune-mediated responses. It is one of the important causes of dilated cardiomyopathy worldwide. The diagnosis is presumed on clinical presentation and noninvasive diagnostic methods such as cardiovascular magnetic resonance imaging. Endomyocardial biopsy remains the gold standard for in vivo diagnosis of myocarditis. The therapeutic and prognostic benefits of endomyocardial biopsy results have recently been demonstrated in several clinical trials. Although remarkable advances in diagnosis, understanding of pathophysiological mechanisms, and treatment of acute myocarditis were gained during the last years, no standard treatment strategies could be defined as yet, apart from standard heart failure therapy and physical rest. In severe cases, mechanical support or heart transplantation may become necessary. There is some evidence that immunosuppressive and immunomodulating therapy are effective for chronic, virus-negative inflammatory cardiomyopathy. Further investigations by controlled, randomized studies are needed to definitively determine their role in the treatment of myocarditis.

References

Mar 1, 1991·The Journal of Clinical Investigation·J M Lemire, D C Archer
Oct 1, 1990·The Journal of Infectious Diseases·R KhatibF E Smith
Oct 19, 1989·The New England Journal of Medicine·J E ParrilloD Alling
Aug 1, 1988·Journal of the American College of Cardiology·S RezkallaR Khatib
Nov 1, 1985·Journal of the American College of Cardiology·M R Costanzo-NordinP J Scanlon
Apr 1, 1988·Journal of the American College of Cardiology·D W AndersonJ E Parrillo
Jan 1, 1994·Circulation·N A DruckerJ W Newburger
Nov 14, 1997·Journal of the American College of Cardiology·B LauerH P Schultheiss
Mar 25, 1999·Japanese Heart Journal·H NakashimaK Yano
Dec 10, 1999·Lancet·J G KilianD S Celermajer
Mar 9, 2000·The New England Journal of Medicine·R E McCarthyK L Baughman
Jul 18, 2000·Journal of the American College of Cardiology·G M FelkerJ M Hare
Aug 29, 2001·Circulation·P P Liu, J W Mason
Feb 19, 2002·Journal of the American College of Cardiology·Stephan B FelixKarl Stangl
Jun 28, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G SaurinaLaura DiEugenia
Oct 31, 2003·Lancet·Joseph G MurphyLeslie T Cooper
Dec 20, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Zuyi YuanChiharu Kishimoto
Apr 14, 2004·Circulation·Sabine PankuweitBernhard Maisch
Apr 20, 2005·Journal of the American College of Cardiology·Barry J MaronJames E Udelson
Feb 2, 2006·Circulation·Kenneth L Baughman
Mar 2, 2006·Pharmacology·Punniyakoti T VeeraveeduYoshifusa Aizawa
Aug 10, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·M PauschingerU Kuehl
Sep 26, 2006·American Heart Journal·Alexander StaudtStephan B Felix

❮ Previous
Next ❯

Citations

Sep 27, 2012·Herzschrittmachertherapie & Elektrophysiologie·Philipp Ehlermann, Hugo A Katus
Jan 17, 2013·International Journal of Legal Medicine·Katarzyna MichaudPatrice Mangin
Sep 10, 2013·Current Heart Failure Reports·Michael M Givertz, Douglas L Mann
Oct 26, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert F MillerRashida A Ferrand
Jul 5, 2013·European Heart Journal·Alida L P CaforioUNKNOWN European Society of Cardiology Working Group on Myocardial and Pericardial Diseases
May 10, 2013·Current Opinion in Rheumatology·Jay ReddySally A Huber
Nov 29, 2012·The Pediatric Infectious Disease Journal·Luisa GalliMaurizio de Martino
Jan 9, 2014·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M R HazebroekS Heymans
Jan 1, 2012·Case Reports in Critical Care·Michael BarriePallavi Solanki
Sep 27, 2013·Indian Journal of Pediatrics·R B ShamnaB Lini
Apr 12, 2014·Current Heart Failure Reports·Bernhard MaischSabine Pankuweit
Mar 19, 2014·Forensic Science International : Synergy·Trine Skov NielsenUlrik Thorngren Baandrup
Feb 18, 2014·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Jong-Chan YounSeok-Min Kang
May 28, 2014·Revista Española De Cardiología·Jose Fernando Guadalajara-Boo
May 2, 2014·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Christian UkenaIngrid Kindermann
Dec 20, 2012·Oxidative Medicine and Cellular Longevity·Xiaolong QiJunjie Xiao
Dec 4, 2014·European Journal of Internal Medicine·Ville KytöPäivi Rautava
Oct 14, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Neda RastegarIhab R Kamel
Dec 6, 2014·Magnetic Resonance Imaging Clinics of North America·Juliano Lara Fernandes, Carlos Eduardo Rochitte
Nov 27, 2014·Texas Heart Institute Journal·Santosh K PadalaSandeep Padala
Nov 2, 2012·Heart Failure Reviews·Alida L P CaforioS Iliceto
Jan 23, 2013·Der Radiologe·M GutberletL Lehmkuhl
Nov 21, 2015·Expert Review of Cardiovascular Therapy·Sylvie Di Filippo
Jul 23, 2015·Expert Review of Cardiovascular Therapy·Nasrien Ibrahim, James L Januzzi
Dec 10, 2015·Expert Review of Cardiovascular Therapy·Paul F KantorSteven E Lipshultz
May 29, 2015·Expert Review of Cardiovascular Therapy·Rocio HinojarValentina O Puntmann
Nov 18, 2015·Journal of Veterinary Internal Medicine·R A SantilliM Perego
Dec 2, 2015·Experimental and Therapeutic Medicine·Tao ZhangZhenhua Li
Sep 17, 2014·International Journal of Cardiology·Oliver BorstChristine S Zuern
Sep 26, 2013·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Nuno CabanelasLuís Augusto Providência
Mar 7, 2013·Archivos de cardiología de México·Adrián Bolívar-MejíaOlinda Delgado
Oct 18, 2015·European Heart Journal Cardiovascular Imaging·Julian A LuetkensClaas P Naehle
Feb 26, 2016·International Journal of Cardiology·Yifan FanXinchun Yang
Jan 17, 2015·JACC. Cardiovascular Imaging·Ulf K RadunskiKai Muellerleile
Oct 21, 2015·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Oh Hong KwonMin-Gu Lee
May 24, 2015·Journal of Molecular and Cellular Cardiology·Carolina Jaquenod De GiustiRicardo M Gomez

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Cardiogenic Shock

Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.

Cardiac Glycosides

Cardiac glycosides are a diverse family of naturally derived compounds that bind to and inhibit na+/k+-atpase. Discover the latest research on cardiac glycosides heres.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Current Treatment Options in Cardiovascular Medicine
Maya Guglin, Leelakrishna Nallamshetty
Lancet
Sandeep SagarLeslie T Cooper
Mayo Clinic Proceedings
Jason C SchultzCharanjit S Rihal
The New England Journal of Medicine
Leslie T Cooper
© 2022 Meta ULC. All rights reserved