Update on the use of pramipexole in the treatment of Parkinson's disease.

Neuropsychiatric Disease and Treatment
Radu Constantinescu

Abstract

Pramipexole is a non-ergot dopamine agonist shown to be efficacious in the treatment of Parkinson's disease (PD). This review addresses the literature concerning pramipexole's efficacy in treating motor and non-motor symptoms in PD, its impact on the development of dyskinesias and response fluctuations, the issue of neuroprotection, and the risk for developing adverse events such as increased somnolence, attacks of sudden onset of sleep, cardiac valvulopathy and impulse control disturbances.

Citations

May 6, 2015·Expert Review of Neurotherapeutics·Abdul Qayyum RanaSai Vasan
May 27, 2017·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Adeline Cardon-DunbarGeoffrey K Isbister
Sep 29, 2020·Frontiers in Bioengineering and Biotechnology·Wen Kang ChouMark P Brynildsen
Jun 25, 2016·International Journal of Molecular Sciences·Sumit SarkarSyed Imam
Apr 12, 2017·Journal of Child and Adolescent Psychopharmacology·Ahmed Naguy
Jul 21, 2014·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Mine Silindir, A Yekta Ozer
Jan 12, 2021·Movement Disorders Clinical Practice·Paloma Parra-DíazJuan Carlos Martínez-Castrillo
Aug 29, 2021·Pharmaceuticals·E Maruthi Prasad, Shih-Ya Hung
Oct 15, 2021·CNS Drugs·Sarah MarmolJason Margolesky

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