Updates in vitamin D therapy in cystic fibrosis

Current Opinion in Endocrinology, Diabetes, and Obesity
Trang N Le

Abstract

To summarize recent developments the role of vitamin D and treatment of vitamin D deficiency in cystic fibrosis. Although treatment of low vitamin D levels continues to be important for optimizing bone health in cystic fibrosis, increasing data on the extraskeletal effects of vitamin D are becoming available. Exploratory studies of vitamin D in modulation of respiratory and intestinal microbiomes, and the influence of vitamin D on the metabolomic signature of cystic fibrosis, suggest expanded roles for vitamin D in cystic fibrosis disease and treatment. Emerging developments in cystic fibrosis regarding therapeutics and effects of vitamin D on bone health, inflammation, microbiome, and the metabolome are summarized.

References

Jun 25, 1998·American Journal of Respiratory and Critical Care Medicine·D S DonovanE Shane
Dec 23, 2004·The Journal of Clinical Endocrinology and Metabolism·Robert M ArisTerry B White
May 1, 2007·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Sunghan YimGill Diamond
Feb 21, 2008·Clinical Endocrinology·Linda L WolfendenVin Tangpricha
Nov 5, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sif HansdottirGary W Hunninghake
Feb 12, 2010·International Journal of Endocrinology·William B HallRobert M Aris
Mar 9, 2012·The Journal of Clinical Endocrinology and Metabolism·V TangprichaUNKNOWN Cystic Fibrosis Foundation Vitamin D Evidence-Based Review Committee
Sep 25, 2012·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Darren ShepherdAdam Jaffe
Mar 19, 2014·Journal of Bone and Mineral Metabolism·Shahid SheikhAlpa Patel
Nov 5, 2014·Reproductive Sciences·Julia L FinkelsteinKimberly O O'Brien
Jan 13, 2015·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·William P SexauerAllison M Mallowe
Feb 7, 2015·Pediatric Pulmonology·Michelle B VanstoneThomas O Carpenter
Feb 24, 2015·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Melissa S PutmanJoel S Finkelstein
Feb 20, 2016·American Journal of Physiology. Gastrointestinal and Liver Physiology·Geneviève MorinGeneviève Mailhot
May 4, 2016·Lancet·J Stuart Elborn
Aug 16, 2016·International Journal of Epidemiology·Shakira M NelsonDemetrius Albanes
Oct 23, 2016·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Adèle CoriatiRémi Rabasa-Lhoret
Nov 8, 2016·The Journal of Steroid Biochemistry and Molecular Biology·Mansi KanhereVin Tangpricha
Nov 27, 2016·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Arianna CastoldiClaus-Michael Lehr
Dec 15, 2016·European Journal of Clinical Nutrition·T PincikovaL Hjelte
Jan 29, 2017·The Journal of Steroid Biochemistry and Molecular Biology·Kristina M DiFrancoGill Diamond
Feb 22, 2017·Journal of Pediatric Endocrinology & Metabolism : JPEM·Adela Chirita-EmandiSyed Faisal Ahmed
May 5, 2017·Clinical and Experimental Immunology·T PincikovaL Hjelte
Oct 8, 2017·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Jill Dorsey, Tanja Gonska
Nov 11, 2017·American Journal of Rhinology & Allergy·Iordanis KonstantinidisKonstantinos Markou
Feb 21, 2018·Clinical Nutrition ESPEN·Rhiza Regalado Lam Chew TunCurtis Oleschuk
May 22, 2018·International Journal of Endocrinology·Inger Hee MathiesenMette Friberg Hitz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Susan V Lynch, Oluf Pedersen
BioMed Research International
Domenico SantoroLuca De Nicola
Journal of the Royal Society of Medicine
J O Hunter, R H Warning
Current Opinion in Gastroenterology
Suzanne Devkota, Eugene B Chang
© 2022 Meta ULC. All rights reserved