Upper gastrointestinal tumours in Japanese familial adenomatous polyposis patients

Japanese Journal of Clinical Oncology
Tatsuro YamaguchiKenichi Sugihara

Abstract

The upper gastrointestinal characteristics in Japanese familial adenomatous polyposis patients have not yet been clarified. The aim of the present study was to elucidate these characteristics in Japanese familial adenomatous polyposis patients. This study was conducted by the study group for familial adenomatous polyposis in the Japanese Society for Cancer of the Colon and Rectum. Familial adenomatous polyposis patients who underwent surgical resection from 2000 to 2012 were included in the study. In total, 303 familial adenomatous polyposis patients were enrolled, with 265 cases of classical familial adenomatous polyposis (≥100 adenomas) and 38 cases of attenuated familial adenomatous polyposis (<100 adenomas). Fundic gland polyps were significantly more common in classical familial adenomatous polyposis than in attenuated familial adenomatous polyposis; however, gastric cancer was significantly less common in classical familial adenomatous polyposis than in attenuated familial adenomatous polyposis. Gastric cancer and duodenal adenoma were significantly more common in familial adenomatous polyposis patients with gastric adenoma than in those without gastric adenoma. Duodenal cancer was detected in 7 of 72 familial adenomatous...Continue Reading

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Citations

Mar 9, 2017·Familial Cancer·Sarah-Jane WaltonAndrew Latchford
May 12, 2017·Journal of Medical Genetics·Zeinab GhorbanoghliHans Fa Vasen
Aug 24, 2017·International Journal of Colorectal Disease·Masahiro TanakaKenichi Sugihara
Sep 19, 2019·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Yasuhiro MitsuiTetsuji Takayama
May 25, 2018·Journal of the Anus, Rectum and Colon·Hideyuki IshidaUNKNOWN Japanese Society for Cancer of the Colon and Rectum
Sep 18, 2020·Endoscopy·Isabel MartinAndrew Latchford
Jun 30, 2021·International Journal of Clinical Oncology·Naohiro TomitaUNKNOWN Japanese Society for Cancer of the Colon, Rectum
Jun 20, 2021·Gastrointestinal Endoscopy·Yusaku ShimamotoHideki Ishikawa

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