Uptake of cadmium by rice grown on contaminated soils and its bioavailability/toxicity in human cell lines (Caco-2/HL-7702)

Journal of Agricultural and Food Chemistry
Rukhsanda AzizYang Xiaoe

Abstract

Cadmium (Cd) enters the food chain from polluted soils via contaminated cereals and vegetables; therefore, an understanding of Cd bioaccessibility, bioavailability, and toxicity in humans through rice grain is needed. This study assessed the Cd bioaccessibility, bioavailability, and toxicity to humans from rice grown on Cd-contaminated soils using an in vitro digestion method combined with a Caco-2/HL-7702 cell model. Cadmium bioaccessibility (18.45-30.41%) and bioavailability (4.04-8.62%) were found to be significantly higher in yellow soil (YS) rice than calcareous soil (CS) rice with the corresponding values of 6.89-11.43 and 1.77-2.25%, respectively. Toxicity assays showed an initial toxicity in YS rice at 6 mg kg(-1) Cd, whereas CS rice did not show any significant change due to low Cd concentrations. The acidic soils of Cd-contaminated areas can contribute to a higher dietary intake of Cd. Therefore, it is imperative to monitor Cd concentration in rice to minimize human health risk.

References

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Apr 4, 2014·BioMed Research International·Rukhsanda AzizXiaoe Yang

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Citations

Mar 22, 2016·Environmental Science and Pollution Research International·Muhammad RizwanYong Sik Ok
May 10, 2016·Journal of Food Science·Yinqiang HuoSiming Zhao
Jun 14, 2016·Environmental Science and Pollution Research International·Teresiah Muciku MungaiJun Wang
May 19, 2017·Environmental Science. Processes & Impacts·Tianyuan LiWenzhi Song
Jun 29, 2017·Journal of Agricultural and Food Chemistry·Yanfei DingCheng Zhu
Aug 21, 2019·Environmental Geochemistry and Health·Alexys Giorgia Friol BoimLuís Reynaldo Ferracciú Alleoni
Jun 2, 2020·Journal of Zhejiang University. Science. B·Qin Chen, Fei-Bo Wu
Sep 30, 2020·Journal of Food Science·Lanlan PengYouling L Xiong
Jun 29, 2017·Environmental Science and Pollution Research International·Gaoxiang HuangXingxiang Wang
Jun 27, 2019·Environmental Science and Pollution Research International·Adam Sheka KanuXiangru Tang
Jul 25, 2019·International Journal of Molecular Sciences·Jingguang ChenGuoyou Ye
Dec 17, 2019·Environmental Science and Pollution Research International·Zahra Saeed KhanMuhammad Aleem Sarwar
Aug 21, 2019·BioMed Research International·Mehmood JanMuhammad Jamil
Jan 3, 2021·Journal of Hazardous Materials·Sikhumbuzo Charles KuneneNcobile Bagezile Mdlovu
Nov 24, 2019·The Science of the Total Environment·Wolde Tefera BeriShengke Tian
Jun 11, 2021·Bulletin of Environmental Contamination and Toxicology·Ge-Zi LiGuo-Zhang Kang
Nov 2, 2017·Journal of Agricultural and Food Chemistry·Gaoxiang HuangXingxiang Wang

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