Uptake of interventions to reduce mother-to-child transmission of HIV in the United Kingdom and Ireland

AIDS
D M GibbA E Ades

Abstract

To describe the uptake of interventions to reduce mother-to-child transmission of HIV infection. Voluntary confidential reporting of HIV infection in pregnancy and childhood; telephone interview with key professionals in all London maternity units. HIV-infected pregnant women and children in the United Kingdom and Ireland. Trends in breastfeeding, use of zidovudine, mode of delivery and terminations of pregnancy. Between 1990 and 1995, 14 (4%) out of 314 women diagnosed with HIV infection before delivery breastfed compared with 109 (77%) out of 142 diagnosed after delivery. Since 1994, zidovudine use has increased in each 6-month period (14, 39, 67, and 75%; chi 2 = 17.5, P < 0.001), although in 1995 it was the policy of only 48% of London maternity units to offer zidovudine to HIV-infected women. During 1995, 44% of HIV-infected women were delivered by elective Cesarean section. Since 1990, 20% of women first diagnosed in pregnancy were reported to have their pregnancy terminated. Although detection of previously undiagnosed HIV infection in pregnancy remains low in the United Kingdom, and particularly in London, HIV-infected pregnant women who are aware of their status are increasingly active in taking up interventions to red...Continue Reading

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