PMID: 40384Jan 1, 1979

Uptake of putative neurotransmitters in the organ of Corti

Acta Oto-laryngologica
R L GulleyR J Wenthold


In vitro uptake of putative neurotransmitters into the organ of Corti of the guinea pig was studied by autoradiography. After incubation in 3H-glycine the label was heaviest over the inner hair cell, but was not confined to the synaptic region of the cell. After incubation in 3H-GABA, 3H-glutamate and 3H-aspartate, heavy labeling was seen over the fibers and terminals of the efferent olivocochlear bundle. Leucine, an amino acid not thought to be a neurotransmitter, was uniformly taken up by all cochlear structures. The fact that GABA, glutamate and aspartate are taken up into efferents, which are almost certainly cholinergic, suggests that high affinity uptake of these substances is not restricted to terminals in which these substances are released as neurotransmitters.


Jan 1, 1989·Archives of Oto-rhino-laryngology·P K PlinkertH P Zenner
Jul 1, 1982·Hearing Research·J FexM H Parakkal
Jan 1, 1986·Hearing Research·J Fex, R A Altschuler
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Jun 6, 2003·Brain Research Bulletin·Yehoash Raphael, R A Altschuler
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May 1, 1983·The Annals of Otology, Rhinology, and Laryngology·G K MartinB L Lonsbury-Martin
Jul 1, 1990·Journal of Electron Microscopy Technique·I R Schwartz, A F Ryan
Dec 10, 1983·The Journal of Comparative Neurology·J J GuinanB E Norris
May 1, 1981·Acta Oto-laryngologica·R Klinke


Nov 1, 1975·Acta Oto-laryngologica·C G Wright, R E Preston
Mar 1, 1978·The Annals of Otology, Rhinology, and Laryngology·R P Bobbin, M H Thompson
Feb 1, 1976·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D A GodfreyF M Matschinsky
Feb 11, 1976·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D A GodfreyF M Matschinsky
Jul 15, 1974·Biochemical Pharmacology·L L Iversen
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