Uptake of tritium labelled chloroquine into organized cultures of rat spinal ganglia. An electron microscope autoradiographic study.

Acta Neuropathologica
K Tischner, H A Fischer

Abstract

Cultured spinal ganglia of the rat treated with 3-3H-chloroquine led to the formation of numerous multilamellated bodies (MLB) in the perikarya of neurons, satellite cells, and fibroblasts. Electron microscope autoradiography showed label over and near a considerable proportion of MLB. The action of chloroquine in MLB is discussed with regard to its effect upon lysosomes.

References

Jan 1, 1972·Histochemie. Histochemistry. Histochimie·H A Fischer, G Werner
Jan 7, 1972·Nature·C A HomewoodV C Baggaley
May 27, 1967·Nature·D C Warhurst, D J Hockley
Jul 1, 1972·Journal of Neuropathology and Experimental Neurology·K H Tischner, M R Murray
Apr 1, 1970·Experimental and Molecular Pathology·R Abraham, R J Hendy
Apr 1, 1968·American Journal of Ophthalmology·T LawwillL Altstatt

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