PMID: 8991857Aug 1, 1996Paper

Uptake of yeast (Saccharomyces boulardii) in normal and rotavirus treated intestine

Gut
J Cartwright-ShamoonK E Carr

Abstract

There has recently been a growing interest in the use of the non-pathogenic yeast Saccharomyces boulardii, in the treatment of gastrointestinal disorders, including diarrhoea. The full effects of administration of the yeast are not fully understood. To investigate the morphological effects of inoculated S boulardii on mouse intestinal villi, both in control animals and those treated with rotavirus. Seven day old BALB/c seronegative mice were intubated with either rotavirus (30 microliters orally) or S boulardii (1.5 g/kg) or both rotavirus and S boulardii administered together. Control animals were given saline only. Animals were killed by decapitation 48 hours post-treatment. The middle region of the small intestine was studied using light microscopy and transmission and scanning electron microscopy, including backscattered electron imaging. Animals treated with rotavirus with or without S boulardii developed severe diarrhoea and showed morphological villous changes such as stromal separation and increased epithelial vacuolation. Specimens treated with S boulardii contained yeast particles within the mucosal tissues. The administration of S boulardii did not influence the changes produced by rotavirus, but yeast particles appe...Continue Reading

References

Nov 1, 1978·Proceedings of the Society for Experimental Biology and Medicine·M E LeFevreD D Joel
Jul 1, 1989·Biopharmaceutics & Drug Disposition·H BlehautR H Levy
Mar 1, 1988·Journal of Pediatric Gastroenterology and Nutrition·M P OsborneJ Stephen
Jan 1, 1989·Proceedings of the Society for Experimental Biology and Medicine·M E LeFevreD D Joel
Jan 1, 1988·Infection and Immunity·C L WellsR L Simmons
Jan 1, 1985·Journal of Toxicology and Environmental Health·G L RehnbergJ W Laskey
Oct 1, 1974·Journal of Pharmaceutical Sciences·C PantarottoA Frigerio
Jan 1, 1968·Digestion·G VolkheimerH Wendlandt
Jan 1, 1969·Gut·G VolkheimerU Beitz
Oct 1, 1984·Antimicrobial Agents and Chemotherapy·R D Toothaker, G W Elmer
Nov 1, 1993·The Journal of Pharmacy and Pharmacology·V Dilova, V Shishkova
Sep 1, 1994·Gastroenterology·P C SedmanD Johnstone
Jan 1, 1994·Gut·P A Van LeeuwenR I Wesdorp

❮ Previous
Next ❯

Citations

Aug 16, 2005·International Journal of Food Microbiology·Brunella PosteraroGiovanni Fadda
Sep 26, 2003·Best Practice & Research. Clinical Gastroenterology·Philippe Marteau, Fergus Shanahan
Oct 13, 1998·Alimentary Pharmacology & Therapeutics·S J Lewis, A R Freedman
Jun 1, 2014·PloS One·Silvia LlopisMaría T Fernández-Espinar
May 13, 2008·International Journal of Radiation Biology·Siobhan M MoyesKatharine E Carr
Dec 15, 2015·Revista Argentina de microbiología·Lucia MaffeyLorena Garaicoechea
Jan 14, 2012·Progress in Histochemistry and Cytochemistry·Katharine E CarrSiobhan M Moyes
May 7, 2004·Journal of Clinical Gastroenterology·Vassiliki N NikolopoulouConstantin E Vagianos
Sep 17, 2008·FEMS Yeast Research·Graham H Fleet
Nov 23, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·X WuK Jacobson
Aug 15, 1998·Journal of Clinical Microbiology·M J McCulloughD A Stevens

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.