Urban movement and alcohol intake strongly predict defaulting from tuberculosis treatment: an operational study.

PloS One
Ibrahim SendagireFrank G Cobelens

Abstract

High levels of defaulting from treatment challenge tuberculosis control in many African cities. We assessed defaulting from tuberculosis treatment in an African urban setting. An observational study among adult patients with smear-positive pulmonary tuberculosis receiving treatment at urban primary care clinics in Kampala, Uganda. Defaulting was defined as having missed two consecutive monthly clinic visits while not being reported to have died or continued treatment elsewhere. Defaulting patients were actively followed-up and interviewed. We assessed proportions of patients abandoning treatment with and without the information obtained through active follow-up and we examined associated factors through multivariable logistic regression. Between April 2007 and April 2008, 270 adults aged ≥15 years were included; 54 patients (20%) were recorded as treatment defaulters. On active follow-up vital status was established of 28/54 (52%) patients. Of these, 19 (68%) had completely stopped treatment, one (4%) had died and eight (29%) had continued treatment elsewhere. Extrapolating this to all defaulters meant that 14% rather than 20% of all patients had truly abandoned treatment. Daily consumption of alcohol, recorded at the start of ...Continue Reading

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Aug 17, 2005·Transactions of the Royal Society of Tropical Medicine and Hygiene·Emmanuel Atsu Dodor, Godwin Yao Afenyadu
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Citations

Mar 16, 2013·Tropical Medicine & International Health : TM & IH·T Q LoP A Phillips-Howard
Jan 4, 2017·Revue de pneumologie clinique·E L P BembaJ Mboussa
Dec 7, 2014·Asian Pacific Journal of Tropical Medicine·Isaac AlobuKingsley N Ukwaja
May 30, 2017·The South African Journal of Psychiatry : SAJP : the Journal of the Society of Psychiatrists of South Africa·Samai LaprawatChalermpol Tansakul

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