PMID: 26330884Sep 4, 2015Paper

Urease Inhibitory Activities of some Commonly Consumed Herbal Medicines

Iranian Journal of Pharmaceutical Research : IJPR
Shabnam MaherniaMassoud Amanlou

Abstract

Urease enzyme has a crucial role in the persistent habitation of Helicobacter pylori (H. pylori) that induces gastrointestinal diseases, in particular gastritis, duodenal, peptic ulcer, and gastric cancer. Plants have long been utilized as the biggest source of substances with medicinal properties from natural origin and therefore result in less toxicity and adverse side effects upon usage. 15 medicinal plant extracts were examined against Jack bean urease activity by Berthelot reaction. Each herb was extracted using 80% aqueous methanol. The more effective extracts were further tested and their IC50 values were determined. Three plant extracts including Ginkgo biloba, Rhus coriaria, and Matricaria inodora were found to be the most effective ones with IC50 values of 36.17, 80.29, and 100.6 μg/mL, respectively.

Related Concepts

Related Feeds

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.

Related Papers

Iranian Journal of Pharmaceutical Research : IJPR
Mahmood BiglarFaraz Mojab
Acta gastroenterologica Latinoamericana
R León-Barúa, S Recavarren-Arce
Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva
E de Arzua Zulaica
Enfermedades infecciosas y microbiología clínica
M López-Brea, T Alarcón
© 2021 Meta ULC. All rights reserved