Ureteral calculi detection using low dose computerized tomography protocols is compromised in overweight and underweight patients

The Journal of Urology
Jonathan P HeldtD Duane Baldwin

Abstract

Low dose computerized tomography protocols have demonstrated a reduction in radiation exposure while maintaining excellent sensitivity and specificity in the detection of stones in patients of average size. Low dose computerized tomography protocols have not yet been evaluated in subjects in the extremes of weight. We evaluated the effect of body weight when using low dose protocols to detect ureteral calculi. Three cadavers of increasing weight (55, 85 and 115 kg) were prepared by inserting 721 calcium oxalate stones (range 3 to 7 mm) in 33 random configurations into urinary tracts. Cadavers were then scanned using a GE LightSpeed® at 7 radiation settings. An independent, blinded review by a radiologist was conducted to generate ROC curves, with areas under the curve compared using a 1-way ANOVA (α = 0.05). Sensitivity and specificity were significantly lower in the low and high weight cadavers compared to the medium weight cadaver at 5 mAs (p <0.001) and 7.5 mAs (p = 0.048). Differences in sensitivity and specificity at radiation settings of 15 mAs or greater were not significant. The sensitivity and specificity for the detection of ureteral calculi on computerized tomography were decreased for underweight and overweight subj...Continue Reading

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Oct 20, 2009·The Journal of Urology·Forrest C JellisonD Duane Baldwin

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Citations

Apr 20, 2014·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Tamsin DrakeBhaskar K Somani
Dec 25, 2012·The Journal of Urology·Agnes J WangMichael E Lipkin
Jul 31, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F Dal MoroA Crestani
May 16, 2013·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Chris L MooreAnnette Molinaro
Dec 3, 2014·Annals of Emergency Medicine·Christopher L MooreCary P Gross
Sep 14, 2017·Current Urology Reports·Mohamed A Elkoushy, Sero Andonian

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