Ureterosigmoidostomy associated signet ring colon cancer presenting as hip pain.

Journal of Gastrointestinal Cancer
Rohtesh S MehtaJoseph Whitten

Abstract

We present a case of a young male with a history of ureterosigmoidostomy who presented with hip pain, the subsequent workup of which revealed metastatic bone lesions from a primary sigmoid signet ring cell adenocarcinoma. Review of literature was conducted using databases PubMed Medline (1966-current), PubMed Central (1970-current), and EMBASE (1988-2009) to explore previous studies on the topic; used the Surveillance, Epidemiology and End Results Program for epidemiological data; and used the National Comprehensive Cancer Network guidelines for management recommendations. Ureterosigmoidostomy is well-documented risk factor for colonic neoplasms, the reported incidence being 2-41% with a latent period of 10 to 30 years and a risk of occurrence 80-7,000 times higher than in the general population. The most common histological type of colon cancer seen after ureterosigmoidostomy is adenocarcinoma, but cases of signet-ring cell carcinoma have also been described. Signet-ring cell adenocarcinoma occurs predominantly in stomach but may infrequently arise from other organs such as breast, urinary bladder, and small and large bowel. This case underscores the importance of prolonged screening in patients with ureterosigmoidostomies and...Continue Reading

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Citations

Dec 3, 2014·Chemico-biological Interactions·Hyun-Seuk Moon
Aug 21, 2016·International Journal of Surgery Case Reports·Paulina KuczmaFrédéric Ris
Jan 12, 2017·Acta Cirúrgica Brasileira·Alessandra Marques Dos SantosConceição Aparecida Dornelas
Oct 16, 2019·Case Reports in Oncological Medicine·Farida Abi FarrajFadi Farhat

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