Urethral stent for the treatment of detrusor-sphincter dyssynergia: evaluation of the clinical, urodynamic, endoscopic and radiological efficacy after more than 1 year

The Journal of Urology
P DenysE Chartier-Kastler

Abstract

We studied the intermediate-term clinical, urodynamic, endoscopic and radiological efficacy of the Ultraflex urethral stent (Boston Scientific Co., Boston, Massachusetts) for the treatment of detrusor-sphincter dyssynergia (DSD) in spinal cord injured patients. A total of 47 consecutive men presenting with DSD due to spinal cord injury (39) or various spinal cord diseases (9) were treated with the Ultraflex stent. DSD was demonstrated by urodynamic assessment with electromyographic recording of the striated urethral sphincter muscle activity. Postoperatively, all patients voided by reflex. The number of patients with symptomatic postoperative urinary tract infection decreased significantly (p <0.001). Urodynamic assessment (mean followup +/- SD 2.2 +/- 1.3 years) showed reduction of mean peak detrusor pressure from 65.7 +/- 27.8 to 46.4 +/- 28.8 cm H2O (p <0.005) and reduction of mean residual urine from 231.6 +/- 168.1 to 70.3 +/- 85.6 ml (p <0.0005). Mean urethral closing pressure was markedly reduced from 73.9 +/- 40.9 to 23.8 +/- 25.1 cm H2O (p <0.0005). Mean endoscopic followup was 1.7 +/- 1.1 years. Mean percentage of epithelialization was 90.8% +/- 19.7%, and no obstructive granulation tissue or stone encrustation was ob...Continue Reading

References

Mar 1, 1991·British Journal of Urology·P D McInerneyT P Stephenson
Sep 1, 1990·British Journal of Urology·P J ShawN Mitchell
Sep 1, 1994·The Journal of Urology·M B ChancellorM P Chetner
Feb 25, 2000·The Journal of Urology·K J Weld, R R Dmochowski
Jul 25, 2000·BJU International·E J Chartier-KastlerP Denys
Oct 2, 2002·International Urogynecology Journal and Pelvic Floor Dysfunction·N P GuptaM Aron

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Citations

Mar 31, 2005·Journal of Endourology
May 31, 2014·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·M de Sèze, X Gamé
Jun 27, 2012·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·L EvenX Gamé
Nov 30, 2013·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·E AdamA Ruffion

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