PMID: 11902818Mar 21, 2002Paper

Urinary albumin excretion is independently associated with C-reactive protein levels in overweight and obese nondiabetic premenopausal women

Journal of Internal Medicine
N PannacciulliG De Pergola

Abstract

C-reactive protein (CRP) and microalbuminuria are nowadays considered markers of chronic inflammation of the arterial wall and of endothelial dysfunction, respectively. An increase of CRP levels and of urinary albumin excretion (UAE) rate have both been reported to be independently associated with a higher risk of cardiovascular morbidity and mortality in the general population. The aim of the present study was to evaluate the possible correlation between UAE and CRP concentrations in overweight and obese premenopausal women. A cross-sectional study in a primary care setting. CRP levels and UAE rate were measured in 103 overweight and obese premenopausal women, aged 18-45 years. Other measurements included: central fat accumulation, as evaluated by waist circumference, insulin resistance, as calculated by homeostatic model assessment (HOMAIR); fat-free mass (FFM), as measured by bioimpedance analysis; blood pressure; and fasting plasma levels of glucose, insulin, and lipids. Urinary albumin excretion was positively correlated with body mass index (BMI) (P < 0.01), waist circumference (P < 0.001), diastolic blood pressure (P < 0.01), triglycerides (P < 0.01), HOMAIR (P < 0.05), and CRP levels (P < 0.05); and negatively associate...Continue Reading

References

Apr 1, 1989·Diabetologia·T DeckertA Kofoed-Enevoldsen
Aug 18, 1994·The New England Journal of Medicine·R W Alexander
Jun 1, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·S B SolerteE Ferrari
Jun 11, 1998·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·B AnderssonP Björntorp
Nov 24, 1999·The American Journal of Cardiology·L E RohdeP M Ridker

❮ Previous
Next ❯

Citations

Mar 20, 2003·Current Diabetes Reports·Kevin RowleyJames D Best
Jan 8, 2004·Atherosclerosis·Erik M StuvelingUNKNOWN PREVEND study group
Mar 18, 2003·Diabetes Research and Clinical Practice·Patrick J ManningShirley D Jones
Sep 15, 2005·Current Hypertension Reports·Stephan J L BakkerDick de Zeeuw
Jan 2, 2003·Journal of Endocrinological Investigation·G De Pergola, N Pannacciulli
Mar 8, 2006·Clinical Chemistry and Laboratory Medicine : CCLM·A Erkin BozdemirOya Bayindir
Mar 1, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Erik M StuvelingDick de Zeeuw
Oct 19, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T S BurgertS Caprio
Jul 18, 2008·Diabetes Research and Clinical Practice·I-Te LeeWayne H-H Sheu
Jun 3, 2008·Journal of the Neurological Sciences·Bruce Ovbiagele
Aug 8, 2007·Journal of the Cardiometabolic Syndrome·Chiadi E NdumelePaul M Ridker
Mar 31, 2004·The American Journal of Cardiology·Niranjan SeshadriDennis L Sprecher
Jul 16, 2005·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Murat YilmazHatice Paşaoğlu
Sep 29, 2005·The American Journal of Cardiology·Costas TsioufisIoannis Kallikazaros
Oct 16, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Roberto PedrinelliGiuseppe Penno
Feb 18, 2004·Hypertension·Erik M StuvelingUNKNOWN PREVEND Study Group
Apr 16, 2003·British Journal of Haematology·Lars Møller Pedersen, Peter Grundtvig Sørensen
Jun 11, 2008·The American Journal of Clinical Nutrition·Jennifer A NettletonDavid R Jacobs

❮ Previous
Next ❯

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.