Urinary C-peptide excretion at onset of insulin dependent diabetes mellitus in children

Acta paediatrica Scandinavica
S A IvarssonJ I Thorell

Abstract

The 24-hour urinary excretion of C-peptide and the plasma C-peptide concentration were measured at the onset of insulin dependent diabetes mellitus (IDDM) in children. The excretion of C-peptide was twice as high as that found in normal control subjects, whereas the plasma C-peptide values were markedly lower, indicating increased urinary leakage of C-peptide in this phase of the disease. In the diabetic children under seven years of age the mean value of C-peptide excretion was clearly lower than in the older children.

References

Jan 1, 1978·Diabetes·J Ludvigsson, L G Heding
Jul 1, 1979·Acta paediatrica Scandinavica·E HeinzeE Kleihauer
Jun 1, 1976·Hoppe-Seyler's Zeitschrift für physiologische Chemie·O K FaberC Binder
Jan 1, 1976·Acta Paediatrica Scandinavica. Supplement·P KarlbergI Svennberg-Redegren
Mar 1, 1980·The Journal of Pediatrics·M MenchiniG Chiumello

Related Concepts

Teens
Age Factors
C-Peptide
Circadian Rhythms
Diabetes, Autoimmune

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