Urinary concentrations of parabens and their association with demographic factors: A population-based cross-sectional study

Environmental Research
Hui-Seung KangIn Gyun Hwang

Abstract

Parabens are broad-spectrum antimicrobial agents used in a range of consumer products, including personal care products, cosmetics, and food. Recently, the widespread use of parabens has raised concerns about the potential health risks associated with their endocrine-disrupting effect. In the present study, 2541 urine samples were collected and analyzed by liquid chromatography-mass spectrometry for the determination of the concentrations of methyl paraben (MeP), ethyl paraben (EtP), propyl paraben (PrP) and butyl paraben (BuP). The detection rate and geometric mean concentrations of parabens in the general population followed the order MeP (97.7%; 116ng/mL)>EtP (97.2%; 24.7ng/mL)>PrP (96.7%; 11.0ng/mL)>BuP (83.5%; 1.13ng/mL). The composition profiles showed that MeP and EtP accounted for >90% of the urinary paraben concentration. We performed statistical analysis in order to evaluate differences between demographic variables and urinary concentrations. Our results showed that adjusted proportional change of MeP, PrP, and BuP in adults were 2.67-6.13 times higher in females than in males. The urinary concentrations of PrP in adults increased significantly with age. The adjusted proportional changes of MeP and PrP in adults were...Continue Reading

References

Sep 8, 2004·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Shinshi Oishi
Apr 1, 2005·Journal of Toxicology and Environmental Health. Part a·E GomezC Casellas
Apr 19, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M G SoniG A Burdock
Dec 23, 2006·Environmental Health Perspectives·Xiaoyun YeAntonia M Calafat
Aug 19, 2009·Regulatory Toxicology and Pharmacology : RTP·Christina E Cowan-Ellsberry, Steven H Robison
Jan 9, 2010·Environmental Health Perspectives·Antonia M CalafatLarry L Needham
Apr 13, 2010·Reproductive Toxicology·Julie BobergUlla Hass
Oct 12, 2010·Drug Metabolism and Pharmacokinetics·Suzanne AbbasJacques Magdalou
Mar 17, 2011·Environmental Health Perspectives·Xiaoyun YeAntonia M Calafat
Mar 29, 2011·Environment International·Lidia CasasUNKNOWN INMA Project
Jan 24, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Nicolas AubertJean-Jacques Legrand
Jan 24, 2013·The Science of the Total Environment·Erika S KoeppeJohn D Meeker
Mar 20, 2013·Environmental Science & Technology·Chunyang LiaoKurunthachalam Kannan
Jun 8, 2013·Archives of Environmental Contamination and Toxicology·Wan-Li MaKurunthachalam Kannan
Jun 12, 2013·Environment International·Lei Wang, Kurunthachalam Kannan
Jul 25, 2013·Archives of Environmental Contamination and Toxicology·Ying GuoKurunthachalam Kannan
Jan 8, 2014·Reproduction : the Official Journal of the Society for the Study of Fertility·Hanne FrederiksenAnna-Maria Andersson
Oct 16, 2014·Journal of Korean Medical Science·Ho Seok KooJung Hwan Park
Jan 15, 2015·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ji Young ParkJin Hee Kim
Aug 9, 2015·Environmental Research·Cristina MoretaKurunthachalam Kannan

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Citations

Nov 5, 2016·Neurotoxicology·Leonardo Lara-ValderrábanoEmilio J Galván
Sep 28, 2017·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Yukiko NishihamaHideki Imai
Dec 13, 2019·Environmental Science and Pollution Research International·Isarita MartinsGislaine Ribeiro Pereira
Feb 14, 2020·Environmental Science and Pollution Research International·Yaghoub HajizadehHossein Karimi
Aug 1, 2020·International Journal of Environmental Health Research·Yaghoub HajizadehKarim Ebrahimpour
Feb 12, 2020·Journal of Exposure Science & Environmental Epidemiology·Qiuping WenWei Xia
Jun 24, 2020·Archives of Environmental Contamination and Toxicology·Ghasem Kiani FeizabadiKarim Ebrahimpour
Jun 27, 2018·Toxicological Sciences : an Official Journal of the Society of Toxicology·Thomas L GonzalezJames M Rae
Jan 7, 2020·Journal of Applied Toxicology : JAT·Natalia MatwiejczukMałgorzata M Brzóska
Jun 11, 2020·Scientific Reports·Thomas P van der MeerJana V van Vliet-Ostaptchouk
May 17, 2019·Journal of Water and Health·Asma BeltifaJoris Van Loco
Aug 28, 2020·Environmental Toxicology and Chemistry·Yaghoub HajizadehAwat Feizi
Nov 2, 2018·Environmental Research·Andrea BellaviaUNKNOWN EARTH Study Team
Dec 15, 2020·Journal of Environmental Health Science & Engineering·Ghasem Kiani FeizabadiKarim Ebrahimpour
Dec 15, 2020·Journal of Environmental Health Science & Engineering·Saeid FadaeiRoya Kelishadi
Feb 21, 2021·The Science of the Total Environment·Yang ZhaoShaoyou Lu
Mar 12, 2021·Archives of Environmental Contamination and Toxicology·Yaghoub HajizadehAwat Feizi
Mar 7, 2021·International Journal of Environmental Research and Public Health·Kimberly BergerKim G Harley
Jul 14, 2019·Ecotoxicology and Environmental Safety·Yingxin YuShengtao Ma
Mar 28, 2018·International Journal of Hygiene and Environmental Health·Lesliam Quirós-AlcaláMeleah Boyle
Jul 26, 2017·Talanta·Lucie Kolatorova SosvorovaRichard Hampl
Apr 8, 2021·Journal of Applied Toxicology : JAT·Carmine MerolaMonia Perugini
May 1, 2021·International Journal of Environmental Research and Public Health·Ju-Hee KimWoo-Hyoung Lee
May 26, 2021·The Science of the Total Environment·Fang WeiLiang-Hong Guo
Jun 25, 2021·Environmental Research·Celia MonteagudoAna Rivas
Jun 22, 2021·Journal of Environmental Health Science & Engineering·Xueyan ChenWenbo Li
Aug 5, 2021·Environmental Science & Technology·Kyunghoon KimDeborah H Bennett

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