Urinary Dysfunction in Progressive Supranuclear Palsy Compared with Other Parkinsonian Disorders

PloS One
Tatsuya YamamotoSatoshi Kuwabara

Abstract

Autonomic urinary dysfunction affects patients with progressive supranuclear palsy (PSP); however, the severity and prevalence of urinary dysfunctions in these patients compared with those observed in patients with Parkinson's disease (PD) and multiple system atrophy (MSA) are unknown. We compared urinary dysfunction characteristics in patients with PSP, PD, and MSA. Forty-seven patients who satisfied the probable or possible criteria of the National Institute for Neurological Diseases and Stroke and Society for PSP were assessed using the urinary symptoms questionnaire and the urodynamic study at Chiba and Toho Universities (n = 26 and 21, respectively). The results were compared with those of patients with PD and MSA (n = 218 and 193, respectively). The mean disease duration of PSP and the mean age were 2.97 ± 0.26 and 71.4 ± 0.88 years, respectively. The mini-mental state examination and frontal assessment battery scores were 22.6 ± 0.70 and 10.7 ± 0.49, respectively. Urinary storage and voiding symptoms were observed in 57% and 56% of patients with PSP, respectively. Detrusor overactivity in the urodynamic study was detected in 81% of patients with PSP, which was slightly more than that found in patients with PD (69%) and M...Continue Reading

References

Jun 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·W R Gibb, A J Lees
Oct 19, 2000·Neuropathology : Official Journal of the Japanese Society of Neuropathology·T Mannen
Apr 12, 2002·Neurourology and Urodynamics·Werner SchäferUNKNOWN International Continence Society
Apr 19, 2002·Brain : a Journal of Neurology·Hirohisa WatanabeGen Sobue
Dec 21, 2002·Autonomic Neuroscience : Basic & Clinical·Ryuji SakakibaraTakamichi Hattori
Dec 1, 1963·Acta Physiologica Scandinavica·R GJONE, J SETEKLEIV
Jun 1, 1964·Brain : a Journal of Neurology·J ANDREW, P W NATHAN
Aug 22, 2007·Neurology·L Donker KaatJ C van Swieten
Apr 4, 2008·Brain : a Journal of Neurology·S S O'SullivanA J Lees
May 21, 2008·Nature Reviews. Neuroscience·Clare J FowlerWilliam C de Groat
Sep 10, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Ryuji SakakibaraMasahiko Kishi
Feb 14, 2009·Neurourology and Urodynamics·Tatsuya YamamotoTakamichi Hattori
Feb 24, 2009·Lancet Neurology·David R Williams, Andrew J Lees
Jan 29, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·David R Williams, Andrew J Lees
Feb 16, 2010·Neuroscience Letters·Tatsuya YamamotoSatoshi Kuwabara
Jan 7, 2011·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Fuyuki TatenoTomonori Yamanishi
Jun 15, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Tomoyuki UchiyamaSatoshi Kuwabara
Oct 22, 2011·Neurobiology of Disease·Ryuji SakakibaraTatsuya Yamamoto
Jun 12, 2013·Neurourology and Urodynamics·Tatsuya YamamotoSatoshi Kuwabara
Oct 1, 2012·Journal of Movement Disorders·Sang-Wook Lee, Seong-Beom Koh

❮ Previous
Next ❯

Citations

Feb 7, 2019·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Tomoya KonKoichi Wakabayashi
Jan 2, 2019·Journal of Neurology, Neurosurgery, and Psychiatry·Marcos C B OliveiraThomas T Warner
Jul 18, 2020·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Lawren VandeVredeAdam L Boxer
Oct 6, 2020·Frontiers in Neuroanatomy·Roberta SchellinoAlessandro Vercelli
Jan 29, 2021·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Tianying XingTongwen Ou
Feb 5, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ryuji Sakakibara
Oct 13, 2020·Movement Disorders Clinical Practice·Maria Teresa PellecchiaUNKNOWN Members of the Movement Disorder Society Multiple System Atrophy Study Group
Jul 14, 2021·Expert Review of Neurotherapeutics·Luca MarsiliCarlo Colosimo
Jul 29, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ekawat VichayanratJalesh N Panicker

❮ Previous
Next ❯

Software Mentioned

SPSS Statistics

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.