PMID: 737140Nov 1, 1978Paper

Urinary hippuric acid concentration after occupational exposure to toluene

British Journal of Industrial Medicine
T Wilczok, G Bieniek

Abstract

The results of industrial investigations have shown a correlation between the rate of hippuric acid excretion in a single urine sample collected after daily occupational exposure and the amount of toluene absorbed. The rate of hippuric acid excretion and the average concentration of toluene vapour during exposure time were also related. The quantitative range of the test has been limited to amounts exceeding 425 mg of toluene and concentrations exceeding 69 ppm of toluene in the air because of the physiological presence of hippuric acid in urine. The rate of hippuric acid excretion in urine depends on diuresis and is constant for urinary fractions with diuresis of 30 ml/h. The physiological excretion rate was 20 mg/h with a standard deviation +/- 4.3 mg/h, maximal physiological level 33 mg/h.

References

Mar 1, 1967·American Industrial Hygiene Association Journal·L D Pagnotto, L M Lieberman
Jul 1, 1969·British Journal of Industrial Medicine·M Ikeda, H Ohtsuji

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Citations

Jan 1, 1983·International Archives of Occupational and Environmental Health·R AnderssonJ Sollenberg
Oct 1, 1995·The Journal of Pharmacy and Pharmacology·M AhmadiB P Spragg
May 1, 1981·British Journal of Industrial Medicine·R van DoornP T Henderson
Jan 1, 1985·Journal of Toxicology and Environmental Health·J R FroinesW C Liu
Aug 1, 2006·Ultrasound in Medicine & Biology·Tapio Vehmas, Ari Kaukiainen
Jan 1, 1980·American Journal of Industrial Medicine·E L BakerR G Feldman
Jan 1, 1982·American Journal of Industrial Medicine·D HouthuijsK Biersteker
Apr 14, 2019·Nature Communications·Peter L VoyvodicJerome Bonnet

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