PMID: 3749827Jan 1, 1986Paper

Urinary neopterin index as a measure of rheumatoid activity

Scandinavian Journal of Rheumatology
P HannonenM Oka

Abstract

The urinary neopterin index (U-NEOPT-I), expressed as micro-moles of neopterin/moles of creatinine) of 67 patients with definite or classical rheumatoid arthritis was significantly higher than that of sex- and age-matched persons or of 24 non-matched patients suffering from osteoarthrosis or arthralgia (2p less than 0.001). Furthermore, the patients with active disease had statistically significantly increased U-NEOPT-I when compared with patients with a clinically less active disease. In this study, the U-NEOPT-I value was the equal of CRP as a measure of rheumatoid activity. We suggest that neopterin might be involved in the pathogenesis of rheumatoid arthritis.

References

Jun 1, 1984·Clinical Rheumatology·T MöttönenM Oka
Jan 1, 1982·Immunological Reviews·A CoutinhoS Pettersson
Mar 19, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·A HarmoinenP Grönroos
Feb 1, 1981·Rheumatology and Rehabilitation·R K Mallya, B E Mace

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Citations

Jun 11, 1992·Journal of Autism and Developmental Disorders·I EtoC E Butterworth
Jan 1, 1996·International Journal of Clinical & Laboratory Research·I MazzettiA Facchini
May 11, 2011·Clinical Rheumatology·Yesim OzkanBolkan Simsek
Dec 1, 1988·Mechanisms of Ageing and Development·G ReibneggerK N Traill
Jan 7, 2015·Saudi Journal of Biological Sciences·C K FirozMohammad A Kamal
Jul 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G ReibneggerH Wachter
May 1, 1987·Acta Neurologica Scandinavica·S FredriksonP Eneroth

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